SR12343 - Moligand™, ≥98% , CAS No.2055101-86-3

CAS: 2055101-86-3 Cat. No.: S1447754 Formula: C₁₅H₁₅BrClN₃O Molecular Weight: 368.66

GRADE & PURITY Moligand™, ≥98%

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

SR12343 is a IKK/NF-κB inhibitor and a mimetic of the NF-κB essential modulator (NEMO)-binding domain (NBD). SR12343 inhibits TNF-α- and LPS-induced NF-κB activation by blocking the interaction between IKKβ and NEMO. SR12343 suppresses LPS-induced acute pulmonary inflammation in mice. SR12343 extends the healthspan of naturally aged and accelerated aging mice. SR12343 can be used for research on inflammatory and degenerative diseases

Specifications

Specifications & Purity

Moligand™, ≥98%

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Canonical Smiles: C1=CC(=CC(=C1)Br)CCNC(=O)CNC2=NC=C(C=C2)Cl
• IUPAC Name: N-[2-(3-bromophenyl)ethyl]-2-[(5-chloropyridin-2-yl)amino]acetamide
• InChIKey: PEOFCAIUELALCR-UHFFFAOYSA-N
• INCHI: 1S/C15H15BrClN3O/c16-12-3-1-2-11(8-12)6-7-18-15(21)10-20-14-5-4-13(17)9-19-14/h1-5,8-9H,6-7,10H2,(H,18,21)(H,19,20)
• Molecular Weight: 368.66

Chemical and Physical Properties

• Sensitivity: Light sensitive