🌎 Ship to: United States
Toggle Nav
Cart
Search
Same-day shipping on all in-stock items.
Advanced Search
Quick Order SDS / CoA Structure Bulk & Custom
Menu
Account
Settings
྾
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

MAP3K1

DescriptionMitogen-activated protein kinase kinase kinase 1

Gene and Protein Information

Gene ID4214
Uniprot Accession IDs Q13233
Ensembl ID ENSP00000382423
Symbol MAPKKK1 MEKK MEKK1 MEKK MEKK1 SRXY6 MEKK 1 MAPKKK1
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MAAAAGNRASSSGFPGARATSPEAGGGGGALKASSAPAAAAGLLREAGSGGRERADWRRRQLRKVRSVELDQLPEQPLFLAASPPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGASSPAAAEPGEKRAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPVKGDGSEMNHLAAESPGEVQASAASPASKGRRSPSPGNSPSGRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCARGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPSSLRAAQQQTVQQQPLAGSRRNQESNFNLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGSSGSSPSGGATSGSSQTSISGDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEFPAEFYPHIVSTDVSQAEPVEIRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTTVPHVFSKLLEMLSVSSSTHFTRMRRRLMAIADEVEIAEAIQLGVEDTLDGQQDSFLQASVPNNYLETTENSSPECTVHLEKTGKGLCATKLSASSEDISERLASISVGPSSSTTTTTTTTEQPKPMVQTKGRPHSQCLNSSPLSHHSQLMFPALSTPSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPVFTQSRPLPSSNIHRPKPSRPTPGNTSKQGDPSKNSMTLDLNSSSKCDDSFGCSSNSSNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp471543MAP3K1mitogen-activated protein kinase kinase kinase 19598VGNC:8626OMA, EggNOG
Macaque710979MAP3K1mitogen-activated protein kinase kinase kinase 19544Inparanoid, OMA
Mouse26401Map3k1mitogen-activated protein kinase kinase kinase 110090MGI:1346872Inparanoid, OMA, EggNOG
Rat116667Map3k1mitogen-activated protein kinase kinase kinase 110116RGD:620966Inparanoid, OMA, EggNOG
Dog478061MAP3K1mitogen-activated protein kinase kinase kinase 19615VGNC:42966Inparanoid, OMA, EggNOG
Horse100061688MAP3K1mitogen-activated protein kinase kinase kinase 19796VGNC:19930Inparanoid, OMA, EggNOG
Cow523962MAP3K1mitogen-activated protein kinase kinase kinase 19913VGNC:31188Inparanoid, OMA, EggNOG
Pig396617MAP3K1mitogen-activated protein kinase kinase kinase 19823Inparanoid, OMA, EggNOG
Opossum100032065MAP3K1mitogen-activated protein kinase kinase kinase 113616Inparanoid, OMA, EggNOG
Platypus100076612MAP3K1mitogen-activated protein kinase kinase kinase 19258Inparanoid, OMA, EggNOG
Chicken427144MAP3K1mitogen-activated protein kinase kinase kinase 19031CGNC:10913Inparanoid, OMA, EggNOG
Anole lizard100561745map3k1mitogen-activated protein kinase kinase kinase 128377Inparanoid, OMA, EggNOG
Xenopusmap3k1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-1008434]8364OMA, EggNOG
Zebrafish100334486map3k1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase7955ZDB-GENE-090313-412Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE11 family    /    Mitogen-activated protein kinase kinase kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
      We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.

      Shall we send you a message when we have discounts available?

      Remind me later

      Thank you! Please check your email inbox to confirm.

      Oops! Notifications are disabled.

      Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
      Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
      Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.