TAS0728 - Moligand™, 10 mM in DMSO , CAS No.2088323-16-2
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SKU
T1494521
TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC 50 of 13 nM. TAS0728 also shows IC 50 s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for BMX 、 HER4 、 BLK 、EGFR、 JAK3 、 SLK and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2 , HER3 , and downstream effectors.
More Information
| CAS | 2088323-16-2 |
|---|---|
| Concentration | 10 mM in DMSO |
| Specifications & Purity | Moligand™, 10 mM in DMSO |
| Storage | Store at -80°C |
| Shipped In | Dry ice packs + Cold packs |
| Product Description | TAS0728 is a potent, selective, orally active, irreversible and covalent-binding HER2 inhibitor, with an IC 50 of 13 nM. TAS0728 also shows IC 50 s of 4.9, 8.5, 31, 65, 33, 25 and 86 nM for BMX 、 HER4 、 BLK 、EGFR、 JAK3 、 SLK and LOK respectively. Furthermore, TAS0728 exhibits robust and sustained inhibition of the phosphorylation of HER2 , HER3 , and downstream effectors. |
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