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· · COA & SDS available for every product · Same-day shipping on in-stock items Tavapadon - ≥97% , Dopamine D5 receptor partial agonist, CAS No.1643489-24-0, Dopamine D5 receptor partial agonist
Synonyms
A890906 | UNII-PT4P8MJP8L | (Rac)-Tavapadon | AC-36997 | KS-1260 | PT4P8MJP8L | PF-06649751 | (-)-1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,4(1H,3H)-pyrimidinedione | (-)-1,5-Dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyr
Shipped In
Ice chest + Ice pads
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Why this grade ≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
A890906 | UNII-PT4P8MJP8L | (Rac)-Tavapadon | AC-36997 | KS-1260 | PT4P8MJP8L | PF-06649751 | (-)-1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,4(1H,3H)-pyrimidinedione | (-)-1,5-Dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyr
Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
Tavapadon (PF-6649751, CVL-751) is a partial agonist of dopamine receptor. Tavapadon is useful in the treatment of Parkinson's disease and Alzheimer's.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
PARTIAL AGONIST
Mechanism of action
Dopamine D5 receptor partial agonist
Names and Identifiers Pubchem Sid 528767466 Canonical Smiles CC1=C(C=CC(=C1)OC2=C(C=CC=N2)C(F)(F)F)C3=C(C(=O)NC(=O)N3C)C IUPAC Name 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione InChIKey AKQXQLUNFKDZBN-UHFFFAOYSA-N INCHI 1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17)6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27) Isomeric SMILES CC1=C(C=CC(=C1)OC2=C(C=CC=N2)C(F)(F)F)C3=C(C(=O)NC(=O)N3C)C PubChem CID 86764100 Molecular Weight 391.34
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazines Subclass Pyrimidines and pyrimidine derivatives Intermediate Tree Nodes Not available Direct Parent Phenylpyrimidines Alternative Parents Diarylethers Phenoxy compounds Phenol ethers Toluenes Pyrimidones Pyridines and derivatives Hydropyrimidines Vinylogous amides Heteroaromatic compounds Ureas Lactams Azacyclic compounds Hydrocarbon derivatives Organic oxides Organofluorides Organonitrogen compounds Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents 4-phenylpyrimidine - Diaryl ether - Phenoxy compound - Phenol ether - Pyrimidone - Toluene - Monocyclic benzene moiety - Hydropyrimidine - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Urea - Lactam - Azacycle - Ether - Hydrocarbon derivative - Organonitrogen compound - Organofluoride - Organohalogen compound - Organooxygen compound - Alkyl halide - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Alkyl fluoride - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylpyrimidines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrimidine ring through a CC or CN bond. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 391.300 g/mol XLogP3 3.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 3 Exact Mass 391.114 Da Monoisotopic Mass 391.114 Da Topological Polar Surface Area 71.500 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 665.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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