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A derivative of podophyllotoxin that has shown cytostatic effect & inhibition of topoisomerase II.
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lignans, neolignans and related compounds |
| Class | Lignan lactones |
| Subclass | Podophyllotoxins |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Podophyllotoxins |
| Alternative Parents | Aryltetralin lignans Furanonaphthodioxoles Tetralins Pyranodioxins Dimethoxybenzenes Methoxyphenols Benzodioxoles Anisoles Phenoxy compounds Alkyl aryl ethers 1,3-dioxanes Oxanes Gamma butyrolactones Monosaccharides Tetrahydrofurans Heteroaromatic compounds Thiophenes Carboxylic acid esters 1,2-diols Secondary alcohols Acetals Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Carbonyl compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Podophyllotoxin - 1-aryltetralin lignan - Linear furanonaphthodioxole - Naphthofuran - Methoxyphenol - Pyranodioxin - Tetralin - M-dimethoxybenzene - Dimethoxybenzene - Benzodioxole - Phenoxy compound - Phenol ether - Anisole - Methoxybenzene - Alkyl aryl ether - Phenol - Gamma butyrolactone - Oxane - Meta-dioxane - Monosaccharide - Benzenoid - Monocyclic benzene moiety - Tetrahydrofuran - Heteroaromatic compound - Thiophene - Secondary alcohol - Lactone - 1,2-diol - Carboxylic acid ester - Acetal - Oxacycle - Organoheterocyclic compound - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Ether - Organic oxygen compound - Organooxygen compound - Carbonyl group - Alcohol - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as podophyllotoxins. These are tetralin lignans in which the benzene moiety of the tetralin skeleton is fused to a 1,3-dioxolane and the cyclohexane is fused to a butyrolactone (pyrrolidin-2-one). |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 15, 2025 | T125922 | |
| Certificate of Analysis | Oct 22, 2024 | T125922 | |
| Certificate of Analysis | Mar 15, 2023 | T125922 | |
| Certificate of Analysis | Mar 15, 2023 | T125922 | |
| Certificate of Analysis | Mar 15, 2023 | T125922 | |
| Certificate of Analysis | Mar 15, 2023 | T125922 | |
| Certificate of Analysis | Mar 15, 2023 | T125922 |
| Solubility | Soluble in acetone, dimethyl formamide, methanol (slightly), and DMSO (10 mg/ml). Insoluble in water. |
|---|---|
| Sensitivity | Heat sensitive |
| Specific Rotation[α] | -111° (C=1,CHCl3:MeOH=9:1) |
| Melt Point(°C) | 247 °C(dec.) |
| Molecular Weight | 656.700 g/mol |
| XLogP3 | 1.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 6 |
| Exact Mass | 656.156 Da |
| Monoisotopic Mass | 656.156 Da |
| Topological Polar Surface Area | 189.000 Ų |
| Heavy Atom Count | 46 |
| Formal Charge | 0 |
| Complexity | 1090.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →