Tepoxalin - ≥98% , CAS No.103475-41-8

CAS: 103475-41-8 Cat. No.: T348374 Formula: C20H20ClN3O3 Molecular Weight: 385.84 EC Number: 638-877-2 PubChem CID: 59757
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid | TEPOXALIN [EMA EPAR VETERINARY] | CAS-103475-41-8 | C18362 | SR-01000944187-1 | Tepoxalin (USAN/INN) | BCP23064 | UNII-TZ4OX61974 | Zubrin Rapidly-Disintegrating Tablets |
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Germany (EU)
USA*
Price
Qty
1mg
T348374-1mg
—
3 In stock
€71.94
5mg
T348374-5mg
—
3 In stock
€179.54
10mg
T348374-10mg
—
2 In stock
€268.91
25mg
T348374-25mg
—
2 In stock
€458.08
50mg
T348374-50mg
—
1 In stock
€673.28
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Tepoxalin is a dual inhibitor of COX and 5-lipoxygenase (5-LO) with potent anti-inflammatory activity and a favorable gastrointestinal profile.

Specifications

Synonyms
5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acid | TEPOXALIN [EMA EPAR VETERINARY] | CAS-103475-41-8 | C18362 | SR-01000944187-1 | Tepoxalin (USAN/INN) | BCP23064 | UNII-TZ4OX61974 | Zubrin Rapidly-Disintegrating Tablets |
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid528772065
Canonical SmilesCN(C(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)OC)O
IUPAC Name3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
InChIKeyXYKWNRUXCOIMFZ-UHFFFAOYSA-N
INCHI1S/C20H20ClN3O3/c1-23(26)20(25)12-7-16-13-19(14-3-5-15(21)6-4-14)24(22-16)17-8-10-18(27-2)11-9-17/h3-6,8-11,13,26H,7,12H2,1-2H3
Isomeric SMILES CN(C(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)OC)O
PubChem CID 59757
Molecular Weight 385.84

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassAzoles
SubclassPyrazoles
Intermediate Tree Nodes Not available
Direct ParentPhenylpyrazoles
Alternative Parents Methoxyanilines  Phenoxy compounds  Anisoles  Methoxybenzenes  Alkyl aryl ethers  Chlorobenzenes  Aryl chlorides  Heteroaromatic compounds  Hydroxamic acids  Azacyclic compounds  Hydrocarbon derivatives  Carbonyl compounds  Organic oxides  Organochlorides  Organonitrogen compounds  Organopnictogen compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Phenylpyrazole - Methoxyaniline - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Hydroxamic acid - Carboxylic acid derivative - Azacycle - Ether - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organohalogen compound - Organochloride - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group.
External Descriptors pyrazoles - aromatic ether - monochlorobenzenes - hydroxamic acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALOX5 Tclin Arachidonate 5-lipoxygenase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase (1258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
F2404136Certificate of AnalysisFeb 27, 2024 T348374
F2404137Certificate of AnalysisFeb 27, 2024 T348374
F2404138Certificate of AnalysisFeb 27, 2024 T348374
F2404139Certificate of AnalysisFeb 27, 2024 T348374
F2404140Certificate of AnalysisFeb 27, 2024 T348374
F2404141Certificate of AnalysisFeb 27, 2024 T348374
F2404142Certificate of AnalysisFeb 27, 2024 T348374
F2404143Certificate of AnalysisFeb 27, 2024 T348374
F2404144Certificate of AnalysisFeb 27, 2024 T348374
F2404145Certificate of AnalysisFeb 27, 2024 T348374
Chemical and Physical Properties
SolubilityDMSO: 60 mg/ml (155.5 mM)
Melt Point(°C)123-125° C
Molecular Weight385.800 g/mol
XLogP33.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass385.119 Da
Monoisotopic Mass385.119 Da
Topological Polar Surface Area67.600 Ų
Heavy Atom Count27
Formal Charge0
Complexity479.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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