terevalefim - Moligand™, ≥97% , Hepatocyte growth factor receptor agonist, CAS No.1070881-42-3, Hepatocyte growth factor receptor agonist

CAS: 1070881-42-3 Cat. No.: T614382 Formula: C9H8N2S Molecular Weight: 176.24 PubChem CID: 5714038
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
(E)-3-(2-(thiophen-2-yl)vinyl)-1H-pyrazole | 3-[2-(2-thienyl)ethenyl]-1H-Pyrazole | SNV-003 | (e)-5-(2-(thiophen-2-yl)vinyl)-1h-pyrazole | 5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole | Refanalin | AB09733 | AKOS040755926 | Terevalefim [USAN:INN] | Terevale
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Germany (EU)
USA*
Price
Qty
1mg
T614382-1mg
—
1 In stock
€72.80
5mg
T614382-5mg
—
1 In stock
€216.85
10mg
T614382-10mg
—
1 In stock
€242.88
25mg
T614382-25mg
Made to order · 8–12 wks
€601.26
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor

Specifications

Synonyms
(E)-3-(2-(thiophen-2-yl)vinyl)-1H-pyrazole | 3-[2-(2-thienyl)ethenyl]-1H-Pyrazole | SNV-003 | (e)-5-(2-(thiophen-2-yl)vinyl)-1h-pyrazole | 5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole | Refanalin | AB09733 | AKOS040755926 | Terevalefim [USAN:INN] | Terevale
Specifications & Purity
Moligand™, ≥97%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ACTIVATOR, AGONIST
Mechanism of action
Hepatocyte growth factor receptor agonist
Purity
≥97%
Product Properties
ALogP2.2
Names and Identifiers
Pubchem Sid528768756
Canonical Smilesc1csc(c1)/C=C/c1ccn[nH]1
IUPAC Name5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole
InChIKeyFOHWAQGURRYJFK-ONEGZZNKSA-N
INCHI1S/C9H8N2S/c1-2-9(12-7-1)4-3-8-5-6-10-11-8/h1-7H,(H,10,11)/b4-3+
Isomeric SMILES C1=CSC(=C1)/C=C/C2=CC=NN2
Alternate CAS 500128-99-4
PubChem CID 5714038
Molecular Weight 176.24

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassAzoles
SubclassPyrazoles
Intermediate Tree Nodes Not available
Direct ParentPyrazoles
Alternative Parents Thiophenes  Heteroaromatic compounds  Azacyclic compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Heteroaromatic compound - Thiophene - Pyrazole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyrazoles. These are compounds containing a pyrazole ring, which is a five-member aromatic ring with two nitrogen atoms (at positions 1 and 2) and three carbon atoms.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MET Tclin Hepatocyte growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
C2526633Certificate of AnalysisOct 17, 2024 T614382
C2526634Certificate of AnalysisOct 17, 2024 T614382
C2526635Certificate of AnalysisOct 17, 2024 T614382
C2526636Certificate of AnalysisOct 17, 2024 T614382
C2526637Certificate of AnalysisOct 17, 2024 T614382
C2526638Certificate of AnalysisOct 17, 2024 T614382
C2526639Certificate of AnalysisOct 17, 2024 T614382
Chemical and Physical Properties
Molecular Weight176.240 g/mol
XLogP32.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass176.041 Da
Monoisotopic Mass176.041 Da
Topological Polar Surface Area56.900 Ų
Heavy Atom Count12
Formal Charge0
Complexity170.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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