Thalidomide-O-C2-acid - ≥95%(HPLC) , CAS No.2369068-42-6

CAS: 2369068-42-6 Cat. No.: T287998 Formula: C₁₆H₁₄N₂O₇ Molecular Weight: 346.3 EC Number: 195-665-8 PubChem CID: 139370805

GRADE & PURITY ≥95%(HPLC)

Synonyms

3-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]propanoic acid | Thalidomide 4'-ether-alkylC2-acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

230

Overview

Product description

Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Specifications

Synonyms

3-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]propanoic acid | Thalidomide 4'-ether-alkylC2-acid

Specifications & Purity

≥95%(HPLC)

Biochemical and Physiological Mechanisms

Functionalized cereblon ligand for PROTAC®research and development; incorporates an E3 ligase ligand plus an alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules fo

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(HPLC)

Names and Identifiers

Pubchem Sid

528772859

Canonical Smiles

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCC(=O)O

IUPAC Name

3-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxypropanoic acid

InChIKey

JDORXWYUBMQFIZ-UHFFFAOYSA-N

INCHI

1S/C16H14N2O7/c19-11-5-4-9(14(22)17-11)18-15(23)8-2-1-3-10(13(8)16(18)24)25-7-6-12(20)21/h1-3,9H,4-7H2,(H,20,21)(H,17,19,22)

PubChem CID

139370805

Molecular Weight

346.3