Tolimidone - Moligand™, 10mM in DMSO , Tyrosine-protein kinase Lyn positive allosteric modulator, CAS No.41964-07-2, Tyrosine-protein kinase Lyn positive allosteric modulator

CAS: 41964-07-2 Cat. No.: T580545 Formula: C11H10N2O2 Molecular Weight: 202.21 EC Number: 803-991-5 PubChem CID: 39065
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
MU3JD8E9IS | s8321 | 5-(3-methylphenoxy)-2(1h)-pyrimidinone | HMS3749I15 | AS-16416 | SMR004704144 | GTPL9433 | 5-(m-tolyloxy)pyrimidin-2(1H)-one | NSC-314335 | TOLIMIDONE | NSC314335 | 5-(m-Tolyloxy)-2(1H)-pyrimidinone | A899682 | AC-37077 | BDBM50545405
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Germany (EU)
USA*
Price
Qty
1ml
T580545-1ml
Made to order · 8–12 wks

€232.47

€272.38
Save €39.92 (14.65%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
MU3JD8E9IS | s8321 | 5-(3-methylphenoxy)-2(1h)-pyrimidinone | HMS3749I15 | AS-16416 | SMR004704144 | GTPL9433 | 5-(m-tolyloxy)pyrimidin-2(1H)-one | NSC-314335 | TOLIMIDONE | NSC314335 | 5-(m-Tolyloxy)-2(1H)-pyrimidinone | A899682 | AC-37077 | BDBM50545405
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Selective allosteric activator of Lyn kinase (EC50= 63 nM); displays no significant activity against a range of 47 other kinases, including other Src family kinases such as Fyn, Lck and Src kinase. Reduces blood glucose levels without affectingin vivoinsu
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ALLOSTERIC MODULATOR, POSITIVE ALLOSTERIC MODULATOR
Mechanism of action
Tyrosine-protein kinase Lyn positive allosteric modulator
Product Properties
ALogP1.4
Names and Identifiers
Canonical SmilesCC1=CC(=CC=C1)OC2=CNC(=O)N=C2
IUPAC Name5-(3-methylphenoxy)-1H-pyrimidin-2-one
InChIKeyHJQILFPVRNHTIG-UHFFFAOYSA-N
INCHI1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
Isomeric SMILES CC1=CC(=CC=C1)OC2=CNC(=O)N=C2
WGK Germany 3
Alternate CAS 41964-07-2
PubChem CID 39065
NSC Number 314335
MeSH Entry Terms 5-(3-methylphenoxy)-2(1H)-pyrimidinone;MLR-1023
Molecular Weight 202.21

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassEthers
Intermediate Tree Nodes Not available
Direct ParentDiarylethers
Alternative Parents Phenoxy compounds  Phenol ethers  Toluenes  Pyrimidones  Hydropyrimidines  Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Diaryl ether - Phenoxy compound - Phenol ether - Toluene - Pyrimidone - Monocyclic benzene moiety - Hydropyrimidine - Benzenoid - Pyrimidine - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organic oxide - Organopnictogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
LYN Tclin Tyrosine-protein kinase Lyn (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LYN Tclin Tyrosine-protein kinase Lyn (4251 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
H2625045Certificate of AnalysisAug 28, 2026 T580545
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 20.22, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 4.04, Max Conc. mM: 20
Molecular Weight202.210 g/mol
XLogP31.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass202.074 Da
Monoisotopic Mass202.074 Da
Topological Polar Surface Area50.700 Ų
Heavy Atom Count15
Formal Charge0
Complexity310.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Frequently Asked Questions

How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 41964-07-2, the molecular formula is C11H10N2O2, and the molecular weight is 202.21 g/mol. InChIKey HJQILFPVRNHTIG-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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