TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC 50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actions of PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na 2+ mobilisation fr
IC50& Target:EC50: 10.5 μM (TPC2)
In Vitro:Two-pore channels (TPC1-3) are ancient members of the voltage-gated ion channel superfamily. TPCs are expressed throughout the endo-lysosomal system and regulates the trafficking of various cargoes. TPC2 can mediate different physiological and possib
Biological Activity:TPC2-A1-P is a powerful and membrane permeable agonist of two porexa0channelxa02xa0(TPC2) with an EC 50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actionsxa0ofxa0PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na 2+ mobil
Specifications
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Frequently Asked Questions
How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is T661714(DMSO), the molecular formula is C20H21BrF3NO3, and the molecular weight is 460.28 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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