Tri(2-ethylhexyl)phosphate - ≥99% , CAS No.78-42-2

CAS: 78-42-2 Cat. No.: T104035 Molecular Weight: 434.63 Beilstein Registry Number: 1715839 EC Number: 201-116-6 PubChem CID: 6537
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
GTVWRXDRKAHEAD-UHFFFAOYSA-N | A865029 | Tris-2(2-ethylhexyl)fosfat [Czech] | 1-Hexanol, phosphate | Disflamoll TOF | Phosphoric acid, tris(ethylhexyl) ester | Tris(2-ethylhexy)phosphate | Tris(2-ethylhexyl) phosphate | NSC 407921 | Phosphoric acid, tris(2
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100ml
T104035-100ml
5
$22.90
500ml
T104035-500ml
1

$65.90

$79.90
Save $14.00 (17.52%)
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
GTVWRXDRKAHEAD-UHFFFAOYSA-N | A865029 | Tris-2(2-ethylhexyl)fosfat [Czech] | 1-Hexanol, phosphate | Disflamoll TOF | Phosphoric acid, tris(ethylhexyl) ester | Tris(2-ethylhexy)phosphate | Tris(2-ethylhexyl) phosphate | NSC 407921 | Phosphoric acid, tris(2
Specifications & Purity
≥99%
Storage
Room temperature
Shipped In
Normal
Purity
≥99%
Names and Identifiers
Pubchem Sid504751114
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751114
Canonical SmilesCCCCC(CC)COP(=O)(OCC(CC)CCCC)OCC(CC)CCCC
IUPAC Nametris(2-ethylhexyl) phosphate
InChIKeyGTVWRXDRKAHEAD-UHFFFAOYSA-N
INCHI1S/C24H51O4P/c1-7-13-16-22(10-4)19-26-29(25,27-20-23(11-5)17-14-8-2)28-21-24(12-6)18-15-9-3/h22-24H,7-21H2,1-6H3
Isomeric SMILES CCCCC(CC)COP(=O)(OCC(CC)CCCC)OCC(CC)CCCC
WGK Germany 2
RTECS MP0770000
PubChem CID 6537
Molecular Weight 434.63
Beilstein 1715839

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassOrganic phosphoric acids and derivatives
SubclassPhosphate esters
Intermediate Tree Nodes Alkyl phosphates
Direct ParentTrialkyl phosphates
Alternative Parents Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Trialkyl phosphate - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as trialkyl phosphates. These are organic compounds containing a phosphate group that is linked to exactly three alkyl chains.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot NumberCertificate TypeDateItem
B2626168Certificate of AnalysisJul 04, 2024 T104035
B2628195Certificate of AnalysisJul 04, 2024 T104035
G2416365Certificate of AnalysisJul 04, 2024 T104035
G2416369Certificate of AnalysisJul 04, 2024 T104035
G2416543Certificate of AnalysisJul 04, 2024 T104035
G2416546Certificate of AnalysisJul 04, 2024 T104035
D1614199Certificate of AnalysisJan 10, 2024 T104035
C2302117Certificate of AnalysisDec 30, 2022 T104035
C2302121Certificate of AnalysisDec 30, 2022 T104035
C2302127Certificate of AnalysisDec 30, 2022 T104035
C2302131Certificate of AnalysisDec 30, 2022 T104035
C2302132Certificate of AnalysisDec 30, 2022 T104035
C2427064Certificate of AnalysisDec 30, 2022 T104035
C1907029Certificate of AnalysisDec 14, 2022 T104035
K2202382Certificate of AnalysisNov 07, 2022 T104035
K2202504Certificate of AnalysisNov 04, 2022 T104035

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Chemical and Physical Properties
SensitivityMoisture sensitive.
Refractive Index1.441
Flash Point(°F)215.5℃
Flash Point(°C)215.5℃
Boil Point(°C)216°C
Melt Point(°C)-90°C
Molecular Weight434.600 g/mol
XLogP38.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count21
Exact Mass434.352 Da
Monoisotopic Mass434.352 Da
Topological Polar Surface Area44.800 Ų
Heavy Atom Count29
Formal Charge0
Complexity345.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Qiqi Guo, Yizhi Chen, Peng Zhang, Yusen Liu, Yifan Li, Yu Yang, Qi Cao, Mingzhang Lin.  (2023)  The effects of structural variations in neutral phosphorus extractants on UO22+ extraction behavior and radiation stability: Experimental and theoretical insights.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2023.122785]
2. Jing Song, Chencan Du, Junjie Wang, Yongjin Cui, Yujun Wang, Jian Deng, Guangsheng Luo.  (2022)  A novel observation platform for determining the micro-dispersion performance in practical reaction systems.  Reaction Chemistry & Engineering,  (11): (2322-2333).  [PMID:] [10.1039/D2RE00224H]
3. Bin Lin, Huajing Liu, Chuixiu Huang, Xianjin Xiao, Stig Pedersen-Bjergaard, Xiantao Shen.  (2021)  Versatile Integration of Liquid-Phase Microextraction and Fluorescent Aptamer Beacons: A Synergistic Effect for Bioanalysis.  ANALYTICAL CHEMISTRY,      [PMID:34648282] [10.1021/acs.analchem.1c03600]
4. Chunqing Cai, Fan Yang, Zhigang Zhao, Qiuxia Liao, Ruixi Bai, Wanghuan Guo, Peng Chen, Yang Zhang, Hao Zhang.  (2019)  Promising transport and high-selective separation of Li(I) from Na(I) and K(I) by a functional polymer inclusion membrane (PIM) system.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2019.02.046]
5. Jie Liu, Xiaodong Fan, Xin Min, Xiuzhong Zhu, Na Zhao, Zichao Wang.  (2018)  Synthesis of high cis-1,4 polybutadiene with narrow molecular weight distribution via a neodymium-based binary catalyst.  RSC Advances,  (39): (21926-21932).  [PMID:35541701] [10.1039/C8RA02656D]
6. Dandan Cheng, Yue Liu, Haiqiang Wang, Xiaole Weng, Zhongbiao Wu.  (2015)  Enhanced CO2 adsorptive performance of PEI/SBA-15 adsorbent using phosphate ester based surfactants as additives.  Journal of Environmental Sciences,      [PMID:26702962] [10.1016/j.jes.2015.04.025]
7. Huifang Li, Yu Yue, Xiao Wang, Dahuan Liu.  (2025)  An environmentally friendly lithium extraction system utilizing Cyanex 272 as iron-fixed reagent.  DESALINATION,      [PMID:] [10.1016/j.desal.2025.118574]
8. Junling He, Yong Tang, Chiliang Lin, Shaoyun Peng, Stig Pedersen-Bjergaard, Frederik André Hansen, Chen Zhou.  (2024)  Electromembrane extraction of multi-class prohibited/restricted veterinary drugs from food samples – Exploring liquid membrane composition.  FOOD CHEMISTRY,      [PMID:39733624] [10.1016/j.foodchem.2024.142680]
9. Pengchen Chen, Yali Song, Li Tang, Zhuolin Qiu, Junhui Chen, Siyu Xia, Ashok Iyaswamy, Jing Cai, Yan Sun, Chuanbin Yang, Jigang Wang.  (2024)  Integrated RNA sequencing and biochemical studies reveal endoplasmic reticulum stress and autophagy dysregulation contribute to Tri (2-Ethylhexyl) phosphate (TEHP)-induced cell injury in Sertoli cells.  ENVIRONMENTAL POLLUTION,      [PMID:39029862] [10.1016/j.envpol.2024.124536]
10. Yichen Bu, Yadong Jiang, Zaihua Duan, Wenxin Zeng, Xing Tang, Jingwen Yang, Zhen Yuan, Huiling Tai.  (2025)  Oriented Crystallization of HgTe Quantum Dots with Low Urbach Band-Tail for Broadband Optoelectronic Logic Gates.  Advanced Optical Materials,      [PMID:] [10.1002/adom.202500295]
11. Li Wang, Jianfeng Zhang, Shixin Meng, Huiyong Wu, Yunze Zhao, Zhen Meng, Lei Feng, Huanting Wang, Yuan Cheng, Liangrong Yang, Huizhou Liu.  (2024)  Recovery of lithium from high Mg2+/Li+ ratio brine using a novel solvent extraction system TOP-FeCl3-MIBK.  DESALINATION,      [PMID:] [10.1016/j.desal.2024.118445]
12. Xinying Gong, Junyi Ma, Yang He, Yuxin Dong, Yuanjun Tong, Jiayu Mao, Mao Li, Dongmei Wang, Zhengjun Gong.  (2025)  UV aging and soil organic matter co-regulate the adsorption of organophosphate flame retardants on PVC and PS: Kinetics and mechanisms.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40684501] [10.1016/j.jhazmat.2025.139266]
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