≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application
Tri-n-butylphosphine oxide is used as a catalyst and organic synthesis intermediate. It is also used as a solvent.
| Pubchem Sid | 504752425 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504752425 |
| Canonical Smiles | CCCCP(=O)(CCCC)CCCC |
| IUPAC Name | 1-dibutylphosphorylbutane |
| InChIKey | MNZAKDODWSQONA-UHFFFAOYSA-N |
| INCHI | 1S/C12H27OP/c1-4-7-10-14(13,11-8-5-2)12-9-6-3/h4-12H2,1-3H3 |
| Isomeric SMILES | CCCCP(=O)(CCCC)CCCC |
| WGK Germany | 3 |
| RTECS | SZ1575000 |
| PubChem CID | 13138 |
| UN Number | 1759 |
| Molecular Weight | 218.32 |
| Reaxy-Rn | 1761977 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organophosphorus compounds |
| Class | Organic phosphines and derivatives |
| Subclass | Organophosphine oxides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Organophosphine oxides |
| Alternative Parents | Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Organophosphine oxide - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as organophosphine oxides. These are organic compounds containing the phosphine oxide group, with the general formula R3P=O or R3P+O-. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2228719 | Certificate of Analysis | May 09, 2026 | T100648 |
| J2228706 | Certificate of Analysis | May 09, 2026 | T100648 |
| K2329087 | Certificate of Analysis | Sep 04, 2025 | T100648 |
| K2329086 | Certificate of Analysis | Sep 04, 2025 | T100648 |
| B2210330 | Certificate of Analysis | Aug 20, 2025 | T100648 |
| B2210329 | Certificate of Analysis | Aug 20, 2025 | T100648 |
| D2621107 | Certificate of Analysis | Nov 30, 2024 | T100648 |
| L2411762 | Certificate of Analysis | Nov 30, 2024 | T100648 |
| L2411764 | Certificate of Analysis | Nov 30, 2024 | T100648 |
| L2419011 | Certificate of Analysis | Nov 30, 2024 | T100648 |
| L2419012 | Certificate of Analysis | Nov 30, 2024 | T100648 |
| F2102052 | Certificate of Analysis | Mar 10, 2023 | T100648 |
| H1909171 | Certificate of Analysis | Mar 10, 2023 | T100648 |
| F2102051 | Certificate of Analysis | Mar 09, 2023 | T100648 |
| K2329286 | Certificate of Analysis | Nov 28, 2022 | T100648 |
| J2228641 | Certificate of Analysis | Nov 05, 2022 | T100648 |
| J2228728 | Certificate of Analysis | Nov 05, 2022 | T100648 |
| J2219109 | Certificate of Analysis | Oct 25, 2022 | T100648 |
| G2008023 | Certificate of Analysis | May 11, 2022 | T100648 |
| B2210527 | Certificate of Analysis | Dec 30, 2021 | T100648 |
| Solubility | Soluble in water (56 g/L at 20°C). Soluble in methanol |
|---|---|
| Sensitivity | Hygroscopic.air sensitive |
| Boil Point(°C) | 150°C |
| Melt Point(°C) | 64-69°C |
| Molecular Weight | 218.320 g/mol |
| XLogP3 | 3.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 9 |
| Exact Mass | 218.18 Da |
| Monoisotopic Mass | 218.18 Da |
| Topological Polar Surface Area | 17.100 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 137.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jun-Nan Yang, Tian Chen, Jing Ge, Jing-Jing Wang, Yi-Chen Yin, Yi-Feng Lan, Xue-Chen Ru, Zhen-Yu Ma, Qun Zhang, Hong-Bin Yao. (2021) High Color Purity and Efficient Green Light-Emitting Diode Using Perovskite Nanocrystals with the Size Overly Exceeding Bohr Exciton Diameter. Journal of the American Chemical Society, [PMID:34766754] [10.1021/jacs.1c09948] |
| 2. Zhen-Ya Liu, An-An Liu, Haohao Fu, Qing-Yuan Cheng, Ming-Yu Zhang, Man-Man Pan, Li-Ping Liu, Meng-Yao Luo, Bo Tang, Wei Zhao, Juan Kong, Xueguang Shao, Dai-Wen Pang. (2021) Breaking through the Size Control Dilemma of Silver Chalcogenide Quantum Dots via Trialkylphosphine-Induced Ripening: Leading to Ag2Te Emitting from 950 to 2100 nm. Journal of the American Chemical Society, [PMID:34353027] [10.1021/jacs.1c06661] |
| 3. Qianrui Xu, Yang Wang, Pengcheng Gao, Yong Jiang. (2021) Preparation of “pomegranate”-like QD/SiO2/poly(St-co-MAA) fluorescent nanobeads in two steps to improve stability and biocompatibility. NEW JOURNAL OF CHEMISTRY, 45 (24): (10618-10625). [PMID:] [10.1039/D1NJ00526J] |
