≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
It is a good quencher of tryptophan fluorescence.
It was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.
| Pubchem Sid | 488183998 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488183998 |
| Canonical Smiles | C(=O)(C(F)(F)F)N |
| IUPAC Name | 2,2,2-trifluoroacetamide |
| InChIKey | NRKYWOKHZRQRJR-UHFFFAOYSA-N |
| INCHI | 1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7) |
| Isomeric SMILES | C(=O)(C(F)(F)F)N |
| WGK Germany | 3 |
| PubChem CID | 67717 |
| Molecular Weight | 113.04 |
| Beilstein | 1753625 |
| Reaxy-Rn | 1753625 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Carboxylic acid derivatives |
| Intermediate Tree Nodes | Carboxylic acid amides |
| Direct Parent | Primary carboxylic acid amides |
| Alternative Parents | Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Primary carboxylic acid amide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Carbonyl group - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as primary carboxylic acid amides. These are compounds comprising primary carboxylic acid amide functional group, with the general structure RC(=O)NH2. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2602105 | Certificate of Analysis | Jun 08, 2026 | T110544 |
| E2621139 | Certificate of Analysis | May 25, 2026 | T110544 |
| L2519074 | Certificate of Analysis | Dec 30, 2025 | T110544 |
| L2510053 | Certificate of Analysis | Dec 15, 2025 | T110544 |
| K2514044 | Certificate of Analysis | Nov 24, 2025 | T110544 |
| L2122172 | Certificate of Analysis | Oct 11, 2025 | T110544 |
| L2122173 | Certificate of Analysis | Oct 11, 2025 | T110544 |
| L2122187 | Certificate of Analysis | Oct 11, 2025 | T110544 |
| L2122422 | Certificate of Analysis | Oct 11, 2025 | T110544 |
| I2504594 | Certificate of Analysis | Jun 22, 2024 | T110544 |
| I2308210 | Certificate of Analysis | Sep 13, 2023 | T110544 |
| A2411084 | Certificate of Analysis | Nov 15, 2021 | T110544 |
| D2419072 | Certificate of Analysis | Nov 15, 2021 | T110544 |
| D2502074 | Certificate of Analysis | Nov 15, 2021 | T110544 |
| I2405130 | Certificate of Analysis | Nov 15, 2021 | T110544 |
| L2326063 | Certificate of Analysis | Nov 15, 2021 | T110544 |
| Solubility | Soluble in water (460 mg/ml), alcohol, ether, chloroform (partially), and methanol. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Boil Point(°C) | 162.5°C |
| Melt Point(°C) | 75°C |
| Molecular Weight | 113.040 g/mol |
| XLogP3 | 0.100 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 113.009 Da |
| Monoisotopic Mass | 113.009 Da |
| Topological Polar Surface Area | 43.100 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 85.400 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Qiuying Li, Lili Lian, Xiyue Wang, Runnan Wang, Yuanyuan Tian, Xiaoyang Guo, Dawei Lou. (2017) Analysis of microcystins using high-performance liquid chromatography and magnetic solid-phase extraction with silica-coated magnetite with cetylpyridinium chloride. JOURNAL OF SEPARATION SCIENCE, 40 (8): (1644-1650). [PMID:28195401] [10.1002/jssc.201601407] |
| 2. Chuanjiang Zhou, Xiao Song, Ran Wei, Shengjie Liu, Zhaoqiang Wu, Hong Chen. (2024) A conductive ionogel with Stretchability, low hysteresis and adjustable adhesion for Air/Underwater mechanosensing. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.155992] |
| 3. Chuanjiang Zhou, Ran Wei, Zhaoqiang Wu. (2025) Janus-type hydrophobic conductive ionogel with adjustable adhesion for amphibious strain sensing and triboelectric nanogenerators. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2025.137651] |
| 4. Cai Wen, Zhang Qian-ying, Zhu Peng-cheng, Hu Wanrong, An Hongyue, Huo Dan-Qun, Li Dongliang. (2025) Study on dynamic changes and correlations of microbial diversity, key enzyme activity and conventional components in tobacco leaves during the aging process. Bioresources and Bioprocessing, 12 (1): (1-17). [PMID:41191230] [10.1186/s40643-025-00969-3] |
| 5. Xuetao Yan, Lifei Chen, Yuze Ren, Kaixuan Cui, Tianliang Li, Lixing Lin, Zeyu Li, Haicheng Song, Yingying Chen, Zhenzhen Li, Lingyan Feng. (2026) Explainable Machine Learning for Solvents-Driven G-quartet Circularly Polarized Luminescence Material in Multilevel Anti-counterfeiting. Advanced Optical Materials, [PMID:] [10.1002/adom.71180] |
