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TrkA-IN-3 - ≥98% , CAS No.T659232
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC 50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC . TrkA-IN-3 can be used for the research of pain.
Appearance:Solid
IC50& Target:TrkA 22.4 nM (IC 50 )
In Vitro:TrkA-IN-3 (compound 5) demonstrates 73.9% and 64.8% of kinase inhibition towards TrkA at concentrations of 1 μM and 0.1 μM , respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Biological Activity:TrkA-IN-3 is a potent, subselective and allosteric TrkA inhibitor, with an IC 50 of 22.4 nM. TrkA-IN-3 shows more than 8000-fold selectivity for TrkA over TrkB and TrkC . TrkA-IN-3 can be used for the research of pain.
Specifications
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
| Canonical Smiles | CN1C=CC(C2=CC(C(NC3=CC(C(O)=O)=CN=C3C4=CC=CC=C4)=O)=CC=C2C(F)(F)F)=N1 |
|---|---|
| Molecular Weight | 466.41 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 50 mg/mL (107.20 mM; Need ultrasonic) |
|---|
Solution Calculators
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