Valproic acid-d15 - ≥99%,≥99 atom% D , CAS No.362049-65-8

CAS: 362049-65-8 Cat. No.: V650220 Molecular Weight: 159.30

GRADE & PURITY ≥99%,≥99 atom% D

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Specifications

Specifications & Purity

≥99%, ≥99 atom% D

Biochemical and Physiological Mechanisms

Valproic acid-d 15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor , with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2 . Valpro

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%, ≥99 atom% D

Names and Identifiers

• Isomeric SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C(=O)O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
• Alternate CAS: 99-66-1(unlabelled)
• Molecular Weight: 159.30