Vincamine - Moligand™, 10 mM in DMSO , CAS No.1617-90-9

CAS: 1617-90-9 Cat. No.: V1499465 Formula: C₂₁H₂₆N₂O₃ Molecular Weight: 354.44 Beilstein Registry Number: 25(3/4)1252 EC Number: 216-576-3 PubChem CID: 15376

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle . Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo , and has the potential for the type 2 diabetes mellitus (T2DM) research.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Product Properties

• ALogP: 2.9

Names and Identifiers

• Isomeric SMILES: CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O
• WGK Germany: 3
• RTECS: YY8575000
• PubChem CID: 15376
• Molecular Weight: 354.44
• Beilstein: 25(3/4)1252

Chemical and Physical Properties

• Specific Rotation[α]: 43° (C=1,Pyridine)
• Melt Point(°C): 232°C

References

1. Yu-Chen Jiang, Jia Guo, Sai-Hu Liu, Xu Dai, Chen-Yu Wang, Li-Hua Lian, Zhen-Yu Cui, Ji-Xing Nan, Yan-Ling Wu.  (2025)  Vincamine ameliorates hepatic fibrosis via inhibiting S100A4-mediated farnesoid X receptor activation: based on liver microenvironment and enterohepatic circulation dependence.  BRITISH JOURNAL OF PHARMACOLOGY,      [PMID:39940076] [10.1111/bph.17471]

Frequently Asked Questions

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1617-90-9, the molecular formula is C21H26N2O3, and the molecular weight is 354.44 g/mol.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.