WZ811 - 10mM in DMSO , CAS No.55778-02-4

CAS: 55778-02-4 Cat. No.: W409079 Formula: C₁₈H₁₈N₄ Molecular Weight: 290.36 EC Number: 694-750-1 PubChem CID: 11565518

GRADE & PURITY 10mM in DMSO

Synonyms

1,4-Benzenedimethanamine, N1,N4-di-2-pyridinyl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

WZ811 is a highly potent competitiveCXCR4antagonist withEC50of 0.3 nM.
In vitro

WZ811 is a highly potent competitive antagonist of CXCR4. WZ811 is effective in counteracting SDF-1 on cAMP reduction at doses as low as a few nanomoles. WZ811 blocks SDF-1-mediated invasion with EC50 of 5.2 nM.

In vivo

Cell Data

cell lines：Primary human osteoblasts cell lines

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

1,4-Benzenedimethanamine, N1,N4-di-2-pyridinyl-

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3
• WGK Germany: 3
• PubChem CID: 11565518
• Molecular Weight: 290.36

Associated Targets(Human)

CXCR4 Tclin C-X-C chemokine receptor type 4 (3 Activities)

Discover Target: CXCR4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 55 mg/mL (199.13 mM); Water: 55 mg/mL (199.13 mM); Ethanol: 55 mg/mL (199.13 mM)
• Melt Point(°C): 190 °C