Z-DEVD-AFC - BioReagent, ≥98% , CAS No.1135416-11-3
In stock
SKU
Z647630
Z-DEVD-AFC is a synthetic polypeptide whose core part consists of four amino acids: Asp-Glu-Val-Asp (DEVD), linked to a fluorophore AFC (7-amino-4-trifluoromethylcoumarin). During the process of cell apoptosis, especially when some caspases are activated, Z-DEVD-AFC will be cleaved to release AFC, which emits bright fluorescence and acts as a real-time monitor of the apoptotic process.
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.
More Information
| CAS | 1135416-11-3 |
|---|---|
| Synonyms | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-AFC | Caspase-3 Substrate IV, Fluorogenic |
| Specifications & Purity | BioReagent, ≥98% |
| Stability And Storage | Store at -20℃ long term (24 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated. |
| Storage | Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Product Description | Z-DEVD-AFC is a synthetic polypeptide whose core part consists of four amino acids: Asp-Glu-Val-Asp (DEVD), linked to a fluorophore AFC (7-amino-4-trifluoromethylcoumarin). During the process of cell apoptosis, especially when some caspases are activated, Z-DEVD-AFC will be cleaved to release AFC, which emits bright fluorescence and acts as a real-time monitor of the apoptotic process. Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.
|
| Solubility | Soluble in 30% ACN/H2O. |
| Molecular Formula | C38H30F3N5O14 |
Reviews
Customer Reviews
Alternative Products
-
Ac-DEVD-AFCStarting at €121.40
-
Z-DEVD-AMCStarting at €258.50
- Ac-WEHD-AMC, TFA salt
Starting at €78.01
Remind me later