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A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin (AFC) derivative has better membrane permeability than the 7-amido-4-methylcoumarin (AMC) derivative.A fluorogenic substrate for caspase 3; has better membrane permeability than the 7-amido-4-methylcoumarin derivative.
| CAS | 201608-14-2 |
|---|---|
| Sinónimos | N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin | NAc-Asp-Glu-Val-Asp-AFC | Ac-Asp-Glu-Val-Asp-AFC |
| Especificaciones y pureza | BioReagent, ≥98% |
| Estabilidad y almacenamiento | Store at -20℃ long term (24 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated. |
| Condiciones de almacenamiento de almacenamiento | Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing |
| Enviado en | Ice chest + Ice pads |
| Product Description | A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin (AFC) derivative has better membrane permeability than the 7-amido-4-methylcoumarin (AMC) derivative.A fluorogenic substrate for caspase 3; has better membrane permeability than the 7-amido-4-methylcoumarin derivative. |
| Solubilidad | Soluble in 20% ACN/H2O. |
| PubChem CID | 644234 |
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