ALDH1A3-IN-1 - ≥98% , CAS No.1695970-90-1

CAS: 1695970-90-1 Cat. No.: A648564 Fórmula: C₁₃H₁₈BrNO Peso molecular: 284.19

CALIDAD & PUREZA ≥98%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC 50 of 0.63 µM and a K i of 0.46 µM. ALDH1A3-IN-1 can be studied in prostate cancer

In Vitro

ALDH1A3-IN-1 (Compound 14) (0-200 µM, 96 h) shows antiproliferative activity in prostate cancer cell lines. ALDH1A3-IN-1 (0-200 µM, 72 h) reduces cell viability of primary prostate cells in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: PC3, LNCaP, and DU145 cells Concentration: 12.5-200 µM Incubation Time: 96 h Result: Showed antiproliferative activity with IC 50 values of 47 ± 6, 25 ± 1, and 61 ± 5 µM against PC3, LNCaP, and DU145 cells. Cell Viability AssayCell Line: Primary cells cultured at early passage from human prostate tissue biopsies Concentration: 50 and 200 μM Incubation Time: 72 h Result: Resulted a dose-dependent reduction in percentage cell viability of primary prostate epithelial cultures.

Form:Liquid

IC50& Target:ALDH1A3 0.63 μM (IC 50 ) ALDH1A1 7.08 μM (IC 50 ) ALDH3A1 8.00 μM (IC 50 ) ALDH1A3 0.46 μM (Ki) ALDH1A3 26.92 μM (Km)

Especificaciones

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC 50 of 0.63 µM and a K i of 0.46 µM. ALDH1A3-IN-1 can be studied in prostate cancer.

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

Peso molecular

284.19

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1695970-90-1, the molecular formula is C13H18BrNO, and the molecular weight is 284.19 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.