Nitrogen-containing aromatic heterocycles

Indazole is a nitrogen-containing aromatic heterocycle formed by the fusion of a benzene ring with a pyrazole ring. Its value in medicinal chemistry does not lie merely in the fact that it “contains two nitrogen atoms” or that “a variety of biological activities have been reported.” ...

In medicinal chemistry, agrochemistry, and materials chemistry, nitrogen-containing aromatic heterocycles are frequently used to “fine-tune a molecule’s character”: while preserving the stability of an aromatic scaffold, introducing nitrogen atoms reshapes electron distribution, polarity, ...