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· · COA & SDS available for every product · Same-day shipping on in-stock items GNE-0877 - Moligand™, ≥98% , Inhibitor of leucine rich repeat kinase 2, CAS No.1374828-69-9, Inhibitor of leucine rich repeat kinase 2
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
BCP09654 | CCG-267909 | compound 11 [PMID: 24354345] | SY275739 | AT19318 | GTPL9393 | TVT | 1H-PYRAZOLE-1-ACETONITRILE, .ALPHA.,.ALPHA.,3-TRIMETHYL-4-((4-(METHYLAMINO)-5-(TRIFLUOROMETHYL)-2-PYRIMIDINYL)AMINO)- | MS-25163 | ANGHS285FG | 2-Methyl-2-[3-meth
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BCP09654 | CCG-267909 | compound 11 [PMID: 24354345] | SY275739 | AT19318 | GTPL9393 | TVT | 1H-PYRAZOLE-1-ACETONITRILE, .ALPHA., .ALPHA., 3-TRIMETHYL-4-((4-(METHYLAMINO)-5-(TRIFLUOROMETHYL)-2-PYRIMIDINYL)AMINO)- | MS-25163 | ANGHS285FG | 2-Methyl-2-[3-meth
Specifications & Purity
Moligand™, ≥98%
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of leucine rich repeat kinase 2
Names and Identifiers Pubchem Sid 504771953 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504771953 Canonical Smiles CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N IUPAC Name 2-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyrazol-1-yl]propanenitrile InChIKey ZPPUMAMZIMPJGP-UHFFFAOYSA-N INCHI 1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22) Isomeric SMILES CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N Alternate CAS 1374828-69-9 MeSH Entry Terms 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile;GNE-0877 Molecular Weight 339.32 Reaxy-Rn 22546856 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22546856&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazines Subclass Pyrimidines and pyrimidine derivatives Intermediate Tree Nodes Not available Direct Parent Aminopyrimidines and derivatives Alternative Parents Imidolactams Pyrazoles Heteroaromatic compounds Nitriles Azacyclic compounds Organofluorides Hydrocarbon derivatives Amines Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Aminopyrimidine - Imidolactam - Azole - Heteroaromatic compound - Pyrazole - Carbonitrile - Azacycle - Nitrile - Alkyl fluoride - Organofluoride - Organohalogen compound - Organonitrogen compound - Hydrocarbon derivative - Cyanide - Organic nitrogen compound - Amine - Alkyl halide - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as aminopyrimidines and derivatives. These are organic compounds containing an amino group attached to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 339.320 g/mol XLogP3 2.500 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 4 Exact Mass 339.142 Da Monoisotopic Mass 339.142 Da Topological Polar Surface Area 91.500 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 486.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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