Ciclo celular/Daño en el ADN - Miosina IIA Supplier | High Purity

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N8-[(2S)-3,3-dimethylbutan-2-yl]-N2-[2-methoxy-4-(1-methyl-1H-pyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine, Inhibitor of TTK protein kinase
CAS: 1578244-34-4 Fórmula: C₂₄H₂₉N₇O Peso molecular: 431.5334

Moligand™ ? ≥97%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: N174563
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Nombre IUPAC

8-N-[(2S)-3,3-dimethylbutan-2-yl]-2-N-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine

SMILES

CC(C(C)(C)C)NC1=NC=CC2=CN=C(N=C21)NC3=C(C=C(C=C3)C4=CN(N=C4)C)OC

InChIKey
XTJZKALDRPVFSN-HNNXBMFYSA-N

InChI

1S/C24H29N7O/c1-15(24(2,3)4)28-22-21-17(9-10-25-22)12-26-23(30-21)29-19-8-7-16(11-20(19)32-6)18-13-27-31(5)14-18/h7-15H,1-6H3,(H,25,28)(H,26,29,30)/t1show more
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Mps1-IN-1 dihydrochloride
CAS: 1883548-93-3 PubChem CID: 91691119 Fórmula: C₂₈H₃₃N₅O₄S.₂HCl Peso molecular: 608.58

≥98%(HPLC)

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: M287223
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Nombre IUPAC

1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol;dihydrochloride

SMILES

CC(C)S(=O)(=O)C1=CC=CC=C1NC2=CC(=NC3=C2C=CN3)NC4=C(C=C(C=C4)N5CCC(CC5)O)OC.Cl.Cl

InChIKey
HFJLUXGXTPNYTQ-UHFFFAOYSA-N

InChI

1S/C28H33N5O4S.2ClH/c1-18(2)38(35,36)26-7-5-4-6-23(26)30-24-17-27(32-28-21(24)10-13-29-28)31-22-9-8-19(16-25(22)37-3)33-14-11-20(34)12-15-33;;/h4-10,1show more

Sinónimos
1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidin...
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AZ 3146, Inhibitor of TTK protein kinase
CAS: 1124329-14-1 Fórmula: C₂₄H₃₂N₆O₃ Peso molecular: 452.55

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A127268
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Nombre IUPAC

9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one

SMILES

CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC

InChIKey
YUKWVHPTFRQHMF-UHFFFAOYSA-N

InChI

1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,show more

Sinónimos
AKOS024457919 | SW219317-1 | HY-14710 | CCG-264989 | AZ3146 | AZ-3146 | 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperid...
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TC Mps1 12
CAS: 1206170-62-8 PubChem CID: 70682875 Fórmula: C₁₇H₂₀N₆O Peso molecular: 324.38

≥99%(HPLC)

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T287052
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Nombre IUPAC

4-[[4-amino-6-(tert-butylamino)-5-cyanopyridin-2-yl]amino]benzamide

SMILES

CC(C)(C)NC1=C(C(=CC(=N1)NC2=CC=C(C=C2)C(=O)N)N)C#N

InChIKey
XDEFNAWAKYQBQY-UHFFFAOYSA-N

InChI

1S/C17H20N6O/c1-17(2,3)23-16-12(9-18)13(19)8-14(22-16)21-11-6-4-10(5-7-11)15(20)24/h4-8H,1-3H3,(H2,20,24)(H4,19,21,22,23)

Sinónimos
4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide
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BAY 1217389, Dual specificity protein kinase TTK inhibitor
CAS: 1554458-53-5 Fórmula: C₂₇H₂₄F₅N₅O₃ Peso molecular: 561.50

10mM in DMSO

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: B421851
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Nombre IUPAC

N-cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-(3,3,3-trifluoropropylamino)imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

SMILES

CC1=C(C=CC(=C1)C2=CN=C3N2N=C(C=C3NCCC(F)(F)F)OC4=C(C(=C(C=C4)OC)F)F)C(=O)NC5CC5

InChIKey
WNEILUNVMHVMPH-UHFFFAOYSA-N

InChI

1S/C27H24F5N5O3/c1-14-11-15(3-6-17(14)26(38)35-16-4-5-16)19-13-34-25-18(33-10-9-27(30,31)32)12-22(36-37(19)25)40-21-8-7-20(39-2)23(28)24(21)29/h3,6-8,show more

Sinónimos
AKOS032944938 | AC-36064 | HY-12859 | NSC787026 | NSC-787026 | BAY1217389 | BAY-1217389 | GTPL12705 | M964LB1114 | EX...
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BAY 1217389, Dual specificity protein kinase TTK inhibitor
CAS: 1554458-53-5 Fórmula: C₂₇H₂₄F₅N₅O₃ Peso molecular: 561.50

Solid Moligand™ ? ≥99%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: B413947
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Nombre IUPAC

N-cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-(3,3,3-trifluoropropylamino)imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

SMILES

CC1=C(C=CC(=C1)C2=CN=C3N2N=C(C=C3NCCC(F)(F)F)OC4=C(C(=C(C=C4)OC)F)F)C(=O)NC5CC5

InChIKey
WNEILUNVMHVMPH-UHFFFAOYSA-N

InChI

1S/C27H24F5N5O3/c1-14-11-15(3-6-17(14)26(38)35-16-4-5-16)19-13-34-25-18(33-10-9-27(30,31)32)12-22(36-37(19)25)40-21-8-7-20(39-2)23(28)24(21)29/h3,6-8,show more

Sinónimos
AKOS032944938 | AC-36064 | HY-12859 | NSC787026 | NSC-787026 | BAY1217389 | BAY-1217389 | GTPL12705 | M964LB1114 | EX...
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BOS172722
CAS: 1578245-44-9 Fórmula: C₂₄H₃₀N₈O Peso molecular: 446.55

10mM in DMSO

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: B421892
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Nombre IUPAC

8-N-(2,2-dimethylpropyl)-2-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine

SMILES

CCOC1=C(C=CC(=C1)C2=NN=CN2C)NC3=NC=C4C=C(N=C(C4=N3)NCC(C)(C)C)C

InChIKey
SGWLRDAOCLITOM-UHFFFAOYSA-N

InChI

1S/C24H30N8O/c1-7-33-19-11-16(22-31-27-14-32(22)6)8-9-18(19)29-23-25-12-17-10-15(2)28-21(20(17)30-23)26-13-24(3,4)5/h8-12,14H,7,13H2,1-6H3,(H,26,28)(Hshow more

Sinónimos
compound 36 [PMID: 30199249] | s8911 | 1578245-44-9 | N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl...
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BOS172722
CAS: 1578245-44-9 Fórmula: C₂₄H₃₀N₈O Peso molecular: 446.55

≥99%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: B414264
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Nombre IUPAC

8-N-(2,2-dimethylpropyl)-2-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine

SMILES

CCOC1=C(C=CC(=C1)C2=NN=CN2C)NC3=NC=C4C=C(N=C(C4=N3)NCC(C)(C)C)C

InChIKey
SGWLRDAOCLITOM-UHFFFAOYSA-N

InChI

1S/C24H30N8O/c1-7-33-19-11-16(22-31-27-14-32(22)6)8-9-18(19)29-23-25-12-17-10-15(2)28-21(20(17)30-23)26-13-24(3,4)5/h8-12,14H,7,13H2,1-6H3,(H,26,28)(Hshow more

Sinónimos
compound 36 [PMID: 30199249] | s8911 | 1578245-44-9 | N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl...
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Empesertib (BAY1161909), Dual specificity protein kinase TTK inhibitor
CAS: 1443763-60-7 Fórmula: C₂₉H₂₆FN₅O₄S Peso molecular: 559.61

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: E413946
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Nombre IUPAC

(2R)-2-(4-fluorophenyl)-N-[4-[2-(2-methoxy-4-methylsulfonylanilino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide

SMILES

CC(C1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)C3=CN4C(=NC(=N4)NC5=C(C=C(C=C5)S(=O)(=O)C)OC)C=C3

InChIKey
NRJKIOCCERLIDG-GOSISDBHSA-N

InChI

1S/C29H26FN5O4S/c1-18(19-4-9-22(30)10-5-19)28(36)31-23-11-6-20(7-12-23)21-8-15-27-33-29(34-35(27)17-21)32-25-14-13-24(40(3,37)38)16-26(25)39-2/h4-18H,show more

Sinónimos
A908652 | (-)-BAY-1161909 | Benzeneacetamide, 4-fluoro-N-[4-[2-[[2-methoxy-4-(methylsulfonyl)phenyl]amino][1,2,4]tria...
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MPI-0479605, Inhibitor of TTK protein kinase
CAS: 1246529-32-7 Fórmula: C₂₂H₂₉N₇O Peso molecular: 407.51

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: M413761
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Nombre IUPAC

6-N-cyclohexyl-2-N-(2-methyl-4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

SMILES

CC1=C(C=CC(=C1)N2CCOCC2)NC3=NC4=C(C(=N3)NC5CCCCC5)NC=N4

InChIKey
OVJBNYKNHXJGSA-UHFFFAOYSA-N

InChI

1S/C22H29N7O/c1-15-13-17(29-9-11-30-12-10-29)7-8-18(15)26-22-27-20-19(23-14-24-20)21(28-22)25-16-5-3-2-4-6-16/h7-8,13-14,16H,2-6,9-12H2,1H3,(H3,23,24,show more

Sinónimos
N6-cyclohexyl-N2-(2-methyl-4-morpholinophenyl)-9H-purine-2,6-diamine
Lista de deseos Añadir para comparar
MPI-0479605, Inhibitor of TTK protein kinase
CAS: 1246529-32-7 Fórmula: C₂₂H₂₉N₇O Peso molecular: 407.51

Moligand™ ? 10mM in DMSO

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: M421046
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Nombre IUPAC

6-N-cyclohexyl-2-N-(2-methyl-4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

SMILES

CC1=C(C=CC(=C1)N2CCOCC2)NC3=NC4=C(C(=N3)NC5CCCCC5)NC=N4

InChIKey
OVJBNYKNHXJGSA-UHFFFAOYSA-N

InChI

1S/C22H29N7O/c1-15-13-17(29-9-11-30-12-10-29)7-8-18(15)26-22-27-20-19(23-14-24-20)21(28-22)25-16-5-3-2-4-6-16/h7-8,13-14,16H,2-6,9-12H2,1H3,(H3,23,24,show more

Sinónimos
N6-cyclohexyl-N2-(2-methyl-4-morpholinophenyl)-9H-purine-2,6-diamine
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luvixasertib, Inhibitor of TTK protein kinase
CAS: 1610759-22-2 PubChem CID: 118086034

Moligand™ ?

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: L611619
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Nombre IUPAC

N-cyclopropyl-4-[7-[(3-hydroxy-3-methylcyclobutyl)methylamino]-5-pyridin-3-yloxypyrazolo[1,5-a]pyrimidin-3-yl]-2-methylbenzamide

SMILES

Cc1c(ccc(c1)c1c2nc(cc(n2nc1)NCC1CC(C1)(C)O)Oc1cnccc1)C(=O)NC1CC1

InChIKey
PMQUGSPFUBGJCZ-UHFFFAOYSA-N

InChI

1S/C28H30N6O3/c1-17-10-19(5-8-22(17)27(35)32-20-6-7-20)23-16-31-34-24(30-14-18-12-28(2,36)13-18)11-25(33-26(23)34)37-21-4-3-9-29-15-21/h3-5,8-11,15-16show more

Sinónimos
SCHEMBL16729234 | EX-A2577 | CARD-20(22)-ENOLIDE, 3-((6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL)OXY)-1,5,11,14,19-PENTAHYDROXY...

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Preguntas frecuentes

Which compounds are listed for Mps1?

Compounds associated with Mps1 are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.

How does Mps1 sit within Cell Cycle/DNA Damage?

Mps1 is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.

What data should I check before ordering a compound from Mps1?

For compounds listed under Mps1, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

How do I find related targets or backup compounds for Mps1?

Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring Mps1, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.