proteína quinasa 3 activada por mitógenos
47 productos
Productos
- Selonsertib (GS-4997), Mitogen-activated protein kinase kinase kinase 5 inhibitorCAS: 1448428-04-3 Número EC: 822-332-2 PubChem CID: 71245288 Fórmula: C24H24FN7O Peso molecular: 445.49Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Almacén en EE. UU., envío a la EU* Articulo #: S413964Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 5-(4-cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide
- SMILES
- CC1=CC(=C(C=C1N2C=C(N=C2)C3CC3)C(=O)NC4=CC=CC(=N4)C5=NN=CN5C(C)C)F
- InChIKey
- YIDDLAAKOYYGJG-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AMY27913 | HY-18938 | 1448428-04-3 | (2S,SR)-METHIONINE SULFOXIMINE | EX-A1618 | GS 4997 | Selonsertib (GS-4997) | UN...
- Takinib, Inhibitor of CDC like kinase 2;Inhibitor of interleukin 1 receptor associated kinase 1;Inhibitor of interleukin 1 receptor associated kinase 4;Inhibitor of mitogen-activated protein kinase kinase kinase 7CAS: 1111556-37-6 Número EC: 841-675-9 PubChem CID: 37750349 Fórmula: C18H18N4O2 Peso molecular: 322.37Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T420617Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 3-N-(1-propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
- SMILES
- CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
- InChIKey
- UOZVVPXKJGOFIG-UHFFFAOYSA-N
- InChI
- 1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
- Sinónimos
- N17080 | SCHEMBL20063046 | F0918-1884 | A928060 | Tox21_300612 | Diethyl phthalate, 99% | NSC789624 | NSC-789624 | UN...
- pelubiprofenCAS: 69956-77-0 PubChem CID: 5282203Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: P612684Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid
- SMILES
- CC(C1=CC=C(C=C1)C=C2CCCCC2=O)C(=O)O
- InChIKey
- AUZUGWXLBGZUPP-GXDHUFHOSA-N
- InChI
- 1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+
- Sinónimos
- (+-)-p-(((E)-2-Oxocyclohexylidene)methyl)hydratropic acid | CAS-69956-77-0 | DB12150 | Q27251763 | Benzeneacetic acid...
- Cot inhibitor-1◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: C646885Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- PF-05381941CAS: 1474022-02-0 Fórmula: C27H26N6O2 Peso molecular: 466.53◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: P647400Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- TAK1/MAP4K2 inhibitor 1◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: T648184Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]benzamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F
- InChIKey
- RWNAOXLCVXJMGM-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AKOS016012030 | n-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-((6-methyl-7h-pyrrolo[2,3-...
- DLK-IN-1Solid ≥98%◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: D650308Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 5-[5-[(1R,5S)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethoxy)pyridin-2-amine
- SMILES
- CC(C)N1C(=CC(=N1)C2=CC(=C(N=C2)N)OC(F)(F)F)C3C4C3CN(C4)C5COC5
- InChIKey
- UHEFRVBGJORHNV-UUVAVEHKSA-N
- InChI
- show more
- SM1-71◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: S646519Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NC(=O)C=C)Cl
- InChIKey
- SCMLGVPMSXTUNC-UHFFFAOYSA-N
- InChI
- show more
- GNE-3511Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: G647232Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile
- SMILES
- C1CN(CCC1C2=CC(=NC(=C2)N3CCC(C3)(F)F)NC4=NC=CC(=C4)C#N)C5COC5
- InChIKey
- RHFIAUKMKYHHFA-UHFFFAOYSA-N
- InChI
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- Sinónimos
- 2-((6-(3,3-Difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile
- ASK1-IN-2◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: A648376Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 6-fluoro-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]-1H-indole-2-carboxamide
- SMILES
- CC(C)N1C=NN=C1C2=NC(=CC=C2)NC(=O)C3=CC4=C(N3)C=C(C=C4)F
- InChIKey
- LYUQNMNUBOUCBX-UHFFFAOYSA-N
- InChI
- 1S/C19H17FN6O/c1-11(2)26-10-21-25-18(26)14-4-3-5-17(23-14)24-19(27)16-8-12-6-7-13(20)9-15(12)22-16/h3-11,22H,1-2H3,(H,23,24,27)
- TAK1-IN-4CAS: 1570374-32-1 Fórmula: C18H17N3O3 Peso molecular: 323.35◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: T649901Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- SMILES
- O=C(C1=CC=CC(C(NC2=NC3=C(N2CCC)C=CC=C3)=O)=C1)O
- Cot inhibitor-2◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: C650545Vista del artículoPrecios y tamaños del paquete
Identificadores técnicos
- Nombre IUPAC
- 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile
- SMILES
- CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC4=C(C(=CN=C4C(=C3)Cl)C#N)NC5=CC(=C(C=C5)F)Cl
- InChIKey
- PHNZIIMWDVXPGG-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- BDBM29923 | 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-c...
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Preguntas frecuentes
How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.