Vía MAPK/ERK - proteína quinasa 3 activada por mitógenos Supplier | High Purity

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(5Z)-7-Oxozeaenol, Inhibitor of mitogen-activated protein kinase kinase kinase 7
CAS: 253863-19-3 Número EC: 683-694-3 Fórmula: C₁₉H₂₂O₇ Peso molecular: 362.37

Solid Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: Z286693
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Nombre IUPAC

(4S,6Z,9S,10S,12E)-9,10,18-trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione

SMILES

COc1cc(O)c2C(=O)O[C@@H](C)CC=CC(=O)[C@@H](O)[C@@H](O)C\C=C\c2c1

InChIKey
NEQZWEXWOFPKOT-BYRRXHGESA-N

InChI

1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3-/t11-,15-,18+show more

Sinónimos
5Z-7-Oxozeaenol | AKOS030213203 | 5Z-7-Oxozeaenol, >=98% (HPLC) | NCGC00186421-07 | N-iodosuccinic acid imide | BDBM5...
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Oleanolic acid, Agonist of GPBA receptor
CAS: 508-02-1 Número EC: 208-081-6 Fórmula: C₃₀H₄₈O₃ Peso molecular: 456.7

Solid Moligand™ ? ≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: O110088
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Nombre IUPAC

(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acshow more

SMILES

CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C

InChIKey
MIJYXULNPSFWEK-GTOFXWBISA-N

InChI

1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,show more

Sinónimos
Caryophyllin | OLEANOLIC_ACID | SMR000445561 | Oleanolic acid, analytical standard | OLEANOLIC ACID (CONSTITUENT OF H...
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MSC 2032964A, Inhibitor of mitogen-activated protein kinase kinase kinase 5
CAS: 1124381-43-6 Fórmula: C₁₆H₁₃F₃N₆O Peso molecular: 362.31

Moligand™ ? ≥98%(HPLC)

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: M287311
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Nombre IUPAC

N-[5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]pyridine-3-carboxamide

SMILES

C1CC1NC2=CC(=CC3=NC(=NN23)NC(=O)C4=CN=CC=C4)C(F)(F)F

InChIKey
XUKGFHHTSUKORV-UHFFFAOYSA-N

InChI

1S/C16H13F3N6O/c17-16(18,19)10-6-12(21-11-3-4-11)25-13(7-10)22-15(24-25)23-14(26)9-2-1-5-20-8-9/h1-2,5-8,11,21H,3-4H2,(H,23,24,26)

Sinónimos
N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide | AS-74425 | MRF-0000032 ...
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NQDI 1
CAS: 175026-96-7 Fórmula: C₁₉H₁₃NO₄ Peso molecular: 319.31

≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: N288303
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Nombre IUPAC

ethyl 8,15-dioxo-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-16-carboxylate

SMILES

CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O

InChIKey
UFJGFNHRMPMALC-UHFFFAOYSA-N

InChI

1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)

Sinónimos
2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester | ethyl 2,7-dioxo-3,7-dihydro-2H-na...
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7,3',4'-Trihydroxyisoflavone (7,3',4'-THIF)
CAS: 485-63-2 Número EC: 676-470-1 PubChem CID: 5284648 Fórmula: C₁₅H₁₀O₅ Peso molecular: 270.24

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T276528
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Nombre IUPAC

3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one

SMILES

C1=CC(=C(C=C1C2=COC3=C(C2=O)C=CC(=C3)O)O)O

InChIKey
DDKGKOOLFLYZDL-UHFFFAOYSA-N

InChI

1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H

Sinónimos
Orita-13 | 3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one # | 3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one | 3'...
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TC ASK 10
CAS: 1005775-56-3 PubChem CID: 68661090 Fórmula: C₂₁H₂₁N₅O.2HCl Peso molecular: 432.35

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T287955
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Nombre IUPAC

4-tert-butyl-N-(6-imidazol-1-ylimidazo[1,2-a]pyridin-2-yl)benzamide;dihydrochloride

SMILES

CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CN3C=C(C=CC3=N2)N4C=CN=C4.Cl.Cl

InChIKey
IKKLFEDUYFZNBO-UHFFFAOYSA-N

InChI

1S/C21H21N5O.2ClH/c1-21(2,3)16-6-4-15(5-7-16)20(27)24-18-13-26-12-17(8-9-19(26)23-18)25-11-10-22-14-25;;/h4-14H,1-3H3,(H,24,27);2*1H

Sinónimos
4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride | N-(6-(1H-imidazol...
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Takinib, Inhibitor of CDC like kinase 2;Inhibitor of interleukin 1 receptor associated kinase 1;Inhibitor of interleukin 1 receptor associated kinase 4;Inhibitor of mitogen-activated protein kinase kinase kinase 7
CAS: 1111556-37-6 Número EC: 841-675-9 PubChem CID: 37750349 Fórmula: C₁₈H₁₈N₄O₂ Peso molecular: 322.37

Moligand™ ? ≥98%(HPLC)

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T288176
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Nombre IUPAC

3-N-(1-propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide

SMILES

CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N

InChIKey
UOZVVPXKJGOFIG-UHFFFAOYSA-N

InChI

1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)

Sinónimos
N17080 | SCHEMBL20063046 | F0918-1884 | A928060 | Tox21_300612 | Diethyl phthalate, 99% | NSC789624 | NSC-789624 | UN...
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Phosphocreatine
CAS: 67-07-2 Número EC: 200-643-9 Fórmula: C₄H₁₀N₃O₅P Peso molecular: 211.11

≥92%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P333235
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Nombre IUPAC

2-[methyl-[(E)-N'-phosphonocarbamimidoyl]amino]acetic acid

SMILES

CN(CC(=O)O)C(=NP(=O)(O)O)N

InChIKey
DRBBFCLWYRJSJZ-UHFFFAOYSA-N

InChI

1S/C4H10N3O5P/c1-7(2-3(8)9)4(5)6-13(10,11)12/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12)

Sinónimos
Phosphagen | 020IUV4N33 | Creatine phosphic acid | Glycine, N-(imino(phosphonoamino)methyl)-N-methyl- | AKOS000120761...
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TC-S 7006, Inhibitor of mitogen-activated protein kinase kinase kinase 8
CAS: 871307-18-5 Número EC: 111-094-9 PubChem CID: 9549300 Fórmula: C₂₁H₁₄ClFN₆ Peso molecular: 404.83

Moligand™ ? ≥99%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: T287927
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Nombre IUPAC

4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile

SMILES

C1=CC(=CN=C1)CNC2=NC=C3C(=C2)C(=C(C=N3)C#N)NC4=CC(=C(C=C4)F)Cl

InChIKey
NMEUKWOOQOHUNA-UHFFFAOYSA-N

InChI

1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)

Sinónimos
DTXSID20946032 | 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 4-(3...
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NG25, Inhibitor of C-terminal Src kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of mitogen-activated protein kinase kinase kinase 7;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of SRC proto-oncoge
CAS: 1315355-93-1 Número EC: 110-114-3 Fórmula: C₂₉H₃₀F₃N₅O₂ Peso molecular: 537.58

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: N125272
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Nombre IUPAC

N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

SMILES

CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F

InChIKey
SMPGEBOIKULBCT-UHFFFAOYSA-N

InChI

1S/C29H30F3N5O2/c1-3-36-12-14-37(15-13-36)18-21-6-7-22(17-24(21)29(30,31)32)35-28(38)20-5-4-19(2)26(16-20)39-25-9-11-34-27-23(25)8-10-33-27/h4-11,16-1show more

Sinónimos
AC-35824 | Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]py...
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Oleanolic acid
CAS: 508-02-1 Número EC: 208-081-6 Fórmula: C₃₀H₄₈O₃ Peso molecular: 456.7

Analytical standard ? Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: O110087
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Nombre IUPAC

(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acshow more

SMILES

CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C

InChIKey
MIJYXULNPSFWEK-GTOFXWBISA-N

InChI

1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,show more

Sinónimos
Caryophyllin | OLEANOLIC_ACID | SMR000445561 | Oleanolic acid, analytical standard | OLEANOLIC ACID (CONSTITUENT OF H...
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ASK1-IN-1
CAS: 2411382-24-4 Fórmula: C₁₉H₁₉N₉O₂ Peso molecular: 405.41

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A412921
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Nombre IUPAC

3-methoxy-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]-1-pyrazin-2-ylpyrazole-4-carboxamide

SMILES

CC(C)N1C=NN=C1C2=NC(=CC=C2)NC(=O)C3=CN(N=C3OC)C4=NC=CN=C4

InChIKey
FTPVMITWJIXRGQ-UHFFFAOYSA-N

InChI

1S/C19H19N9O2/c1-12(2)27-11-22-25-17(27)14-5-4-6-15(23-14)24-18(29)13-10-28(26-19(13)30-3)16-9-20-7-8-21-16/h4-12H,1-3H3,(H,23,24,29)

Sinónimos
N-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-3-methoxy-1-(pyrazin-2-yl)-1H-pyrazole-4-carboxamide

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Preguntas frecuentes

How is the MAP3K listing put together?

It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a MAP3K modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for MAP3K compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the MAP3K compound I need is not listed?

Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.