PI3K/Akt/mTOR - PDK-1 Supplier | High Purity

Productos populares

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N-p-Tosyl-L-phenylalanine chloromethyl ketone(TPCK)
CAS: 402-71-1 Número EC: 206-954-6 Fórmula: C₁₇H₁₈ClNO₃S Peso molecular: 351.85

Moligand™ ? ≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T123226
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Nombre IUPAC

N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide

SMILES

CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)CCl

InChIKey
MQUQNUAYKLCRME-INIZCTEOSA-N

InChI

1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1

Sinónimos
TPCK | C02088 | NCGC00016020-01 | O-tert-Butylhydroxylamine hydrochloride, >=99% | N-P-tosyl-L-phenylalanyl chloromet...
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OSU-03012 (AR-12), 3-phosphoinositide dependent protein kinase-1 inhibitor
CAS: 742112-33-0 Fórmula: C₂₆H₁₉F₃N₄O Peso molecular: 460.46

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: O126958
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Nombre IUPAC

2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide

SMILES

C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F

InChIKey
YULUCECVQOCQFQ-UHFFFAOYSA-N

InChI

1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)

Sinónimos
PDK1 inhibitor AR-12 | 9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate | DTXSID50225206 | AS-1...
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PS 48
CAS: 1180676-32-7 PubChem CID: 44141940 Fórmula: C₁₇H₁₅ClO₂ Peso molecular: 286.76

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P343334
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Nombre IUPAC

(Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid

SMILES

C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl

InChIKey
LLJYFDRQFPQGNY-QINSGFPZSA-N

InChI

1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-

Sinónimos
(Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
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PS48
CAS: 1180676-32-7 PubChem CID: 44141940 Fórmula: C₁₇H₁₅ClO₂ Peso molecular: 286.76

≥95%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P274933
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Nombre IUPAC

(Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid

SMILES

C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl

InChIKey
LLJYFDRQFPQGNY-QINSGFPZSA-N

InChI

1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-

Sinónimos
5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid
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BX-795, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of aurora kinase B;Inhibitor of checkpoint kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of inhibitor of nuclear factor kappa B k
CAS: 702675-74-9 Fórmula: C₂₃H₂₆IN₇O₂S Peso molecular: 591.47

Moligand™ ? ≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: B126947
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Nombre IUPAC

N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide

SMILES

C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I

InChIKey
VAVXGGRQQJZYBL-UHFFFAOYSA-N

InChI

1S/C23H26IN7O2S/c24-18-15-27-22(30-20(18)25-9-5-10-26-21(32)19-8-4-13-34-19)28-16-6-3-7-17(14-16)29-23(33)31-11-1-2-12-31/h3-4,6-8,13-15H,1-2,5,9-12H2show more

Sinónimos
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione | AKOS016369934 | AS-16196...
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BX-912, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of checkpoint kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of kinase insert domain receptor;Inhibitor of protein kinase A
CAS: 702674-56-4 Número EC: 809-821-6 Fórmula: C₂₀H₂₃BrN₈O Peso molecular: 471.36

Solid Moligand™ ? ≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: B126138
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Nombre IUPAC

N-[3-[[5-bromo-4-[2-(1H-imidazol-5-yl)ethylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide

SMILES

C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br

InChIKey
DMMILYKXNCVKOJ-UHFFFAOYSA-N

InChI

1S/C20H23BrN8O/c21-17-12-24-19(28-18(17)23-7-6-16-11-22-13-25-16)26-14-4-3-5-15(10-14)27-20(30)29-8-1-2-9-29/h3-5,10-13H,1-2,6-9H2,(H,22,25)(H,27,30)(show more

Sinónimos
HY-11005 | N-(3-((4-((2-(1H-imidazol-4-yl)ethyl)amino)-5-bromopyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide;B...
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GSK2334470, Inhibitor of 3-phosphoinositide dependent protein kinase 1;Inhibitor of aurora kinase A;Inhibitor of aurora kinase B
CAS: 1227911-45-6 Fórmula: C₂₅H₃₄N₈O Peso molecular: 462.59

Moligand™ ? ≥95%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: G126481
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Nombre IUPAC

(3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl]-N-cyclohexyl-6-methylpiperidine-3-carboxamide

SMILES

CC1CCC(CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5

InChIKey
QLPHOXTXAKOFMU-WBVHZDCISA-N

InChI

1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13,15,17-18H,3-9,14H2,1-show more

Sinónimos
AKOS024458000 | Q27077885 | (3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-meth...
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(+)-Dehidroabietylamina [Agente de resolución óptica]
CAS: 1446-61-3 Número EC: 215-899-7 Fórmula: C₂₀H₃₁N Peso molecular: 285.48

≥90%(GC)

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: D154779
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Nombre IUPAC

[(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine

SMILES

CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C

InChIKey
JVVXZOOGOGPDRZ-SLFFLAALSA-N

InChI

1S/C20H31N/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h6,8,12,14,18H,5,7,9-11,13,21H2,1-4H3/t18-,19-,20+/m0/s1

Sinónimos
EPA Pesticide Chemical Code 004206 | 13-Isopropylpodocarpa-8,11,13-trien-15-amine | Amine D | ((1R,4aS,10aR)-7-Isopro...
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(+)-Dehydroabietylamine
CAS: 1446-61-3 Fórmula: C₂₀H₃₁N Peso molecular: 285.48

≥55%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: D290943
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Identificadores técnicos

Nombre IUPAC

[(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine

SMILES

CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C

InChIKey
JVVXZOOGOGPDRZ-SLFFLAALSA-N

InChI

1S/C20H31N/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h6,8,12,14,18H,5,7,9-11,13,21H2,1-4H3/t18-,19-,20+/m0/s1

Sinónimos
EPA Pesticide Chemical Code 004206 | 13-Isopropylpodocarpa-8,11,13-trien-15-amine | Amine D | ((1R,4aS,10aR)-7-Isopro...
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BX517
CAS: 850717-64-5 Fórmula: C₁₅H₁₄N₄O₂ Peso molecular: 282.30

Solid Moligand™ ? ≥98%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: B413488
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Nombre IUPAC

[(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-1H-indol-5-yl]urea

SMILES

CC(=C1C2=C(C=CC(=C2)NC(=O)N)NC1=O)C3=CC=CN3

InChIKey
DFURSNCTQGJRRX-JYRVWZFOSA-N

InChI

1S/C15H14N4O2/c1-8(11-3-2-6-17-11)13-10-7-9(18-15(16)21)4-5-12(10)19-14(13)20/h2-7,17H,1H3,(H,19,20)(H3,16,18,21)/b13-8-

Sinónimos
SB70061 | PDK1 inhibitor 2 | Q27289467 | MS-24008 | BX517(PDK1 inhibitor2) | [(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylid...
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PKD-IN-1 dihydrochloride
CAS: 2308510-39-4 Fórmula: C₁₈H₂₁Cl₃N₄O Peso molecular: 415.74

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: C412927
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Sinónimos
CRT0066101 dihydrochloride
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Chonglou saponin I
CAS: 50773-41-6 Fórmula: C₄₄H₇₀O₁₆ Peso molecular: 855.02

≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: C115866
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Nombre IUPAC

(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-[(1S,2S,4S,5'R,6R,7show more

SMILES

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(O8)CO)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1

InChIKey
LRRDDWMXYOSKIC-IPKCVOQPSA-N

InChI

1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-38(59-39-35(51)33(49)31(47)21(3)5show more

Sinónimos
Polyphyllin I

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Preguntas frecuentes

How is the PDK-1 listing put together?

It draws on reported PDK-1 annotations within PI3K/Akt/mTOR and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a PDK-1 modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the PDK-1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for PDK-1 compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For PDK-1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the PDK-1 compound I need is not listed?

Search by CAS number or SMILES first, since analogs of PDK-1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.