TGF-beta/Smad

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  1. SIS 3 Hydrochloride
    CAS: 521984-48-5 PubChem CID: 16079005 Fórmula: C28H27N3O3•HCl Peso molecular: 489.99
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: S276442
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    Nombre IUPAC
    (E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;hydrochloride
    SMILES
    CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl
    InChIKey
    CDKIEBFIMCSCBB-CALJPSDSSA-N
    InChI
    1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,show more
    Sinónimos
    (E)-1-[6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-...
  2. Pirfenidone
    CAS: 53179-13-8 Número EC: 621-260-7 Fórmula: C12H11NO Peso molecular: 185.22
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(GC)
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P129335
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    Nombre IUPAC
    5-methyl-1-phenylpyridin-2-one
    SMILES
    CC1=CN(C(=O)C=C1)C2=CC=CC=C2
    InChIKey
    ISWRGOKTTBVCFA-UHFFFAOYSA-N
    InChI
    1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
    Sinónimos
    MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone ...
  3. Trimethylamine N-Oxide(TMANO)
    CAS: 1184-78-7 Número EC: 214-675-6 PubChem CID: 1145 Fórmula: C3H9NO Peso molecular: 75.11
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(T)
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T162064
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    Nombre IUPAC
    N,N-dimethylmethanamine oxide
    SMILES
    C[N+](C)(C)[O-]
    InChIKey
    UYPYRKYUKCHHIB-UHFFFAOYSA-N
    InChI
    1S/C3H9NO/c1-4(2,3)5/h1-3H3
    Sinónimos
    Trimethylamine oxide | NSC 408426 | MFCD00002048 | Trimethlamine-N-oxide | Triox | CHEBI:15724 | EN300-396337 | Trime...
  4. Neohesperidin
    CAS: 13241-33-3 Número EC: 236-216-9 Fórmula: C28H34O15 Peso molecular: 610.56
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: N101968
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    Nombre IUPAC
    (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more
    SMILES
    CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O
    InChIKey
    ARGKVCXINMKCAZ-UZRWAPQLSA-N
    InChI
    1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more
    Sinónimos
    (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
  5. N-óxido de trimetilamina-d9
    CAS: 1161070-49-0 PubChem CID: 71752814 Fórmula: C3D9NO Peso molecular: 84.17
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: T336882
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    Nombre IUPAC
    1,1,1-trideuterio-N,N-bis(trideuteriomethyl)methanamine oxide
    SMILES
    C[N+](C)(C)[O-]
    InChIKey
    UYPYRKYUKCHHIB-GQALSZNTSA-N
    InChI
    1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3
    Sinónimos
    Trimethylamine N-oxide-d9 | Trimethylamine-d9 N-Oxide, 98 atom % D, 98% (CP) | 1,1,1-trideuterio-N,N-bis(trideuteriom...
  6. Asiaticoside
    CAS: 16830-15-2 Número EC: 240-851-7 Fórmula: C48H78O19 Peso molecular: 959.12
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A111276
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    Nombre IUPAC
    [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-show more
    SMILES
    CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O
    InChIKey
    WYQVAPGDARQUBT-FGWHUCSPSA-N
    InChI
    1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(show more
    Sinónimos
    (-)-SENECIONINE | NSC-36002 | (2alpha,3beta,4alpha)-2,3,23-TRIHYDROXYURS-12-EN-28-OIC ACID O-6-DEOXY-alpha-L-MANNOPYR...
  7. Ammothamnine
    CAS: 16837-52-8 Número EC: 605-514-4 Fórmula: C15H24N2O2 Peso molecular: 264.36
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A111286
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    Nombre IUPAC
    (1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
    SMILES
    C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
    InChIKey
    XVPBINOPNYFXID-LHDUFFHYSA-N
    InChI
    1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
    Sinónimos
    Pachycarpidine | BDBM50597716 | Oxymatrine | BBL030371 | MLS001215101 | rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodi...
  8. Alantolactone
    CAS: 546-43-0 Fórmula: C15H20O2 Peso molecular: 232.32
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥97%(HPLC)
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A114070
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    Nombre IUPAC
    (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one
    SMILES
    CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C
    InChIKey
    PXOYOCNNSUAQNS-AGNJHWRGSA-N
    InChI
    1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
    Sinónimos
    (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | Q21099633 | DT...
  9. Halofuginone hydrobromide
    CAS: 64924-67-0 Número EC: 694-602-6 Fórmula: C16H17BrClN3O3•HBr Peso molecular: 495.59
    Solid ≥98%(HPLC)
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: H288889
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    Nombre IUPAC
    7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrobromide
    SMILES
    C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br
    InChIKey
    SJUWEPZBTXEUMU-LDXVYITESA-N
    InChI
    1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1
    Sinónimos
    MFCD00017259 | RU-19110 (hydrobromide) | Halofuginone hydrobromide, (-)- | AMY26820 | HY-N1584A | AKOS015920268 | Hal...
  10. Kartogenin
    CAS: 4727-31-5 Fórmula: C20H15NO3 Peso molecular: 317.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: K134657
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    Nombre IUPAC
    2-[(4-phenylphenyl)carbamoyl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
    InChIKey
    SLUINPGXGFUMLL-UHFFFAOYSA-N
    InChI
    1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
    Sinónimos
    KGN | 2-[[1,1'-Biphenyl]-4-ylcarbamoyl]benzoic Acid | 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid | 4'-Phenyl-phthalanil...
  11. R 268712
    CAS: 879487-87-3 PubChem CID: 11703284 Fórmula: C20H18FN5O Peso molecular: 363.39
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: R286557
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    Nombre IUPAC
    2-[4-[2-fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol
    SMILES
    CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO
    InChIKey
    JQGOCCALXFSRHZ-UHFFFAOYSA-N
    InChI
    1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)
    Sinónimos
    SCHEMBL5198271 | C20H18FN5O | NCGC00387472-01 | 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-py...
  12. Neohesperidin
    CAS: 13241-33-3 Número EC: 236-216-9 Fórmula: C28H34O15 Peso molecular: 610.56
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — Almacén en EE. UU., envío a la EU* Articulo #: N140716
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    Identificadores técnicos
    Nombre IUPAC
    (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more
    SMILES
    CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O
    InChIKey
    ARGKVCXINMKCAZ-UZRWAPQLSA-N
    InChI
    1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more
    Sinónimos
    (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
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Preguntas frecuentes

How is the TGF-beta/Smad listing put together?
It draws on reported TGF-beta/Smad annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a TGF-beta/Smad modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the TGF-beta/Smad entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for TGF-beta/Smad compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For TGF-beta/Smad work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the TGF-beta/Smad compound I need is not listed?
Search by CAS number or SMILES first, since analogs of TGF-beta/Smad compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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