Carrier Free,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE),See COA Azide Free,Carrier Free,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Mouse anti Human MUC1/CD227 Antibody, Monoclonal (C595 (NCRC48)), could be used for in vivo administration in mouse xenograft models, IHC, ICC, IF, in vitro cell cytotoxicity assay, WB, Flow and so on.
Application:
in vivo administration in mouse xenograft models: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
in vitro cell cytotoxicity assay: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
Protein Function
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
MUC1/CD227 Mouse mAb (Ab116379) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling MUC1/CD227 (red) with MUC1/CD227 Mouse mAb (Ab116379) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
| Application | Dilution info |
|---|---|
| WB | Use at an assay dependent concentration. |
| IHC | Use at an assay dependent concentration. |
| IF/ICC | Use at an assay dependent concentration. |
| Flow Cytometry | Use at an assay dependent concentration. |
| in vivo administration in mouse xenograft models | Use at an assay dependent concentration. |
| in vitro cell cytotoxicity assay | Use at an assay dependent concentration. |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F1113535 | Certificate of Analysis | May 21, 2026 | Ab116379 |
| ZJ24F1113536 | Certificate of Analysis | May 21, 2026 | Ab116379 |
| ZJ24F1113537 | Certificate of Analysis | May 21, 2026 | Ab116379 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Carrier Free grade guide → View Validated grade guide → View Azide Free grade guide → View PBS Only grade guide →
