NADPH - ≥93% , CAS No.2646-71-1

CAS: 2646-71-1 Cat. No.: N276326 Fórmula: C₂₁H₂₆N₇Na₄O₁₇P₃ · xH₂O Peso molecular: 833.35 (anhydrous basis) Número EC: 220-163-3

GRADE & PURITY ≥93%

Synonyms

NADPH Na4 | TPNH2 Na4 | AS-10522 | C21H26N7O17P3Na4 | A-NADPH | HB4469 | C74369 | MFCD00036263 | Beta-Nicotinamida adenina dinucleótido fosfato reducido sal tetrasódica | NADPH sal tetrasódica (forma reducida) | Dihidronicotinamida-adenina dinucleótido p

Storage

Protegido de la luz,Almacenar a -20°C,Desecado

Shipped In

Hielera + almohadillas de hielo

Descripción general

Conservar a -20°C. Es importante tener en cuenta que este producto es sensible a la luz. Almacenar en la oscuridad. Almacenar en condiciones de desecación.

Specifications

Sinónimos

NADPH Na4 | TPNH2 Na4 | AS-10522 | C21H26N7O17P3Na4 | A-NADPH | HB4469 | C74369 | MFCD00036263 | Beta-Nicotinamida adenina dinucleótido fosfato reducido sal tetrasódica | NADPH sal tetrasódica (forma reducida) | Dihidronicotinamida-adenina dinucleótido p

Especificaciones y pureza

≥93%

Mecanismos bioquímicos y fisiológicos

Coenzima ubicua y agente reductor biológico que actúa como donante de electrones para muchas enzimas redox, incluida la óxido nítrico sintetasa. Se genera por reducción del aceptor de electrones NADP+.

Condiciones de almacenamiento de almacenamiento

Protegido de la luz,Almacenar a -20°C,Desecado

Enviado en

Hielera + almohadillas de hielo

Tipo de acción

INHIBITOR

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. Sin embargo, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥93%

Nombres e identificadores

Pubchem Sid

488201525

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488201525

Sonrisas canónicas

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

IUPAC Name

tetrasodium;[(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-4-hydroxyoxolan-3-yl] phosphate

InChIKey

WYWWVJHQDVCHKF-ITGWJZMWSA-J

INCHI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13-,14-,15-,16-,20-,21-;;;;/m1..../s1

Isómeros SMILES

C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+].[Na+].[Na+]

Peso molecular

833.35 (anhydrous basis)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside 2',5'-bisphosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines Monosaccharide phosphates 6-aminopurines N-substituted nicotinamides Organic pyrophosphates Aminopyrimidines and derivatives Dihydropyridines Alkyl phosphates Imidolactams N-substituted imidazoles Heteroaromatic compounds Vinylogous amides Oxolanes Primary carboxylic acid amides Secondary alcohols Amino acids and derivatives Enamines Oxacyclic compounds Azacyclic compounds Organic oxides Hydrocarbon derivatives Organic zwitterions Carbonyl compounds Primary amines Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside 2',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Nicotinamide-nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - N-substituted nicotinamide - Organic pyrophosphate - Imidazopyrimidine - Purine - Aminopyrimidine - Dihydropyridine - Imidolactam - Alkyl phosphate - Hydropyridine - Pyrimidine - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Vinylogous amide - Azole - Imidazole - Heteroaromatic compound - Oxolane - Carboxamide group - Primary carboxylic acid amide - Secondary alcohol - Amino acid or derivatives - Organoheterocyclic compound - Carboxylic acid derivative - Enamine - Organic alkali metal salt - Azacycle - Oxacycle - Alcohol - Organic zwitterion - Organic sodium salt - Organic salt - Organic oxygen compound - Primary amine - Carbonyl group - Organic oxide - Organooxygen compound - Amine - Organic nitrogen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: 10 mM NaOH: soluble 50 mg/mL, clear
• Sensibilidad: light sensitive;Heat sensitive
• Peso molecular: 833.300 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 22
• Rotatable Bond Count: 12
• Exact Mass: 833.019 Da
• Monoisotopic Mass: 833.019 Da
• Topological Polar Surface Area: 375.000 Ų
• Heavy Atom Count: 52
• Formal Charge: 0
• Complexity: 1380.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 5

XLogP3