Sistema del complemento

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  1. Sutimlimab (anti-C1s), Antibody of complement C1s
    CAS: 2049079-64-1
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab170550
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    C1S
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Umano
    Isotipo
    Human IgG4SP
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Sinonimi
    C1 esterase | Complement component 1 subcomponent s | EC 3.4.21.42
  2. Iptacopan, Complement factor B inhibitor
    CAS: 1644670-37-0 PubChem CID: 90467622 Formula: C25H30N2O4 Peso molecolare: 422.52
    Solido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: I611135
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    Nome IUPAC
    4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid
    SMILES
    CCOC1CCN(C(C1)C2=CC=C(C=C2)C(=O)O)CC3=C(C=C(C4=C3C=CN4)C)OC
    InChIKey
    RENRQMCACQEWFC-UGKGYDQZSA-N
    InChI
    1S/C25H30N2O4/c1-4-31-19-10-12-27(22(14-19)17-5-7-18(8-6-17)25(28)29)15-21-20-9-11-26-24(20)16(2)13-23(21)30-3/h5-9,11,13,19,22,26H,4,10,12,14-15H2,1-show more
    Sinonimi
    WHO 11259 | compound 41 [PMID: 32073845] | IPTACOPAN [WHO-DD] | Z56899081 | JGQ | US9682968, Example-26a | HY-127105 ...
  3. JPE1375, Antagonist of C5a 1 receptor
    CAS: 1254036-23-1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Fabbricato su ordinazione negli USA · 2–4 settimane Oggetto #: rp174390
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    Sinonimi
    JPE 1375
  4. L-156,602, Antagonist of C5a 1 receptor
    CAS: 125228-51-5 PubChem CID: 164201
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Fabbricato su ordinazione negli USA · 2–4 settimane Oggetto #: rp174419
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    SMILES
    CCC(C)CC1CCC(OC1C)(C(C)(C(=O)NC2C(OC(=O)C(N(C(=O)C3CCCNN3C(=O)CNC(=O)C(N(C(=O)C4CCCNN4C2=O)O)C)O)C)C(C)C)O)O
    Sinonimi
    L 156602;PD 124966
  5. PMX53, Antagonist of C5a 1 receptor
    CAS: 219639-75-5 PubChem CID: 6918468 Formula: C47H65N11O7 Peso molecolare: 896.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Fabbricato su ordinazione negli USA · 2–4 settimane Oggetto #: rp174793
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    Nome IUPAC
    (2S)-2-acetamido-N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7show more
    SMILES
    CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C3CCCN3C2=O)CC4CCCCC4)CC5=CNC6=CC=CC=C65)CCCN=C(N)N
    InChIKey
    YOKBGCTZYPOSQM-HPSWDUTRSA-N
    InChI
    1S/C47H65N11O7/c1-29(59)53-37(25-30-13-4-2-5-14-30)42(61)55-36-20-11-22-50-41(60)35(19-10-23-51-47(48)49)54-44(63)39(27-32-28-52-34-18-9-8-17-33(32)34show more
    Sinonimi
    Ac-(cyclo-2,6)-F-[OPdChaWR];PMX 53;PMX-53
  6. PMX205, Antagonist of C5a 1 receptor
    CAS: 514814-49-4 Numero EC: 851-045-5 PubChem CID: 6918845 Formula: C45H62N10O6 Peso molecolare: 839.05
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Fabbricato su ordinazione negli USA · 2–4 settimane Oggetto #: rp174792
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    Nome IUPAC
    N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazashow more
    SMILES
    C1CCC(CC1)CC2C(=O)NC(C(=O)NC(C(=O)NCCCC(C(=O)N3CCCC3C(=O)N2)NC(=O)CCC4=CC=CC=C4)CCCN=C(N)N)CC5=CNC6=CC=CC=C65
    InChIKey
    VATFHFJULBPYLM-ILOBPARPSA-N
    InChI
    1S/C45H62N10O6/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)show more
    Sinonimi
    Cyclic hexapeptide complement C5a antagonist | Hydrocinnamate-(orn-Pro-dcha-Trp-Arg) | SCHEMBL12971708 | EX-A5705 | H...
  7. Avdoralimab (anti-C5AR1), INHIBITOR of C5a anaphylatoxin chemotactic receptor inhibitor
    CAS: 2226393-85-5
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab175459
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    C5AR1
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Umano
    Isotipo
    Human IgG1
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Sinonimi
    ANAPHYLATOXIN RECEPTOR antibody | C5a anaphylatoxin chemotactic receptor antibody | C5a anaphylatoxin receptor antibo...
  8. Lampalizumab (anti-Complement Factor D), Antibody of complement factor D
    CAS: 1278466-20-8
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab175571
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    CFD
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Coniglio, Cynomolgus monkey, Umano
    Isotipo
    Human IgG1
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Sinonimi
    Adipsin antibody | Adipsin/complement factor D antibody | Adn antibody | C3 convertase activator antibody | CFAD_HUMA...
  9. Tesidolumab (anti-Complement C5), BINDING AGENT of Complement C5 binding agent
    CAS: 1531594-08-7
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab176617
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    Associated targets
    C5
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Mouse, Umano
    Isotipo
    Human IgG1
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Sinonimi
    Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 a...
  10. Ravulizumab (anti-Complement C5), INHIBITOR of Complement C5 inhibitor
    CAS: 1803171-55-2
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab176615
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    Associated targets
    C5
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Cynomolgus monkey, Mouse, Scimmia Rhesus, Umano
    Isotipo
    Human IgG2
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Sinonimi
    Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 a...
  11. Eculizumab (anti-Complement C5), INHIBITOR of Complement C5 inhibitor
    CAS: 219685-50-4
    Liquido Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: Ab170870
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    Associated targets
    C5
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2+Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Specie reattive
    Mouse, Umano
    Isotipo
    Human IgG2+Human IgG4
    Specie ospite
    Umano
    Coniugazione
    Unconjugated
    Nome IUPAC
    (2R)-2-[[(2R)-2-amino-3-(1-methoxycarbonylindol-3-yl)propanoyl]-[(2S)-2-[[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino]-4,4-dimethylpentanoyl]aminoshow more
    SMILES
    CCCCC(C(=O)O)N(C(=O)C(CC1=CN(C2=CC=CC=C21)C(=O)OC)N)C(=O)C(CC(C)(C)C)NC(=O)N3C(CCCC3C)C
    InChIKey
    LNGMSNLRAISCCZ-IITZRFRKSA-N
    InChI
    1S/C34H51N5O7/c1-8-9-16-28(31(42)43)39(29(40)25(35)18-23-20-37(33(45)46-7)27-17-11-10-15-24(23)27)30(41)26(19-34(4,5)6)36-32(44)38-21(2)13-12-14-22(38show more
    Sinonimi
    Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 a...
  12. Vemircopan
    CAS: 2086178-00-7 PubChem CID: 126642840 Formula: C29H28BrN7O3 Peso molecolare: 602.48
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: V646867
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    SMILES
    CC1=C(N=C(C=C1)Br)NC(=O)[C@@H]2C[C@]3(C[C@H]3N2C(=O)CN4C5=C(C=C(C=C5)C6=CN=C(N=C6)C)C(=N4)C(=O)C)C
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Domande frequenti

What can I find under Complement System?
This listing collects compounds associated with Complement System within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Complement System?
Consider the reported potency of each Complement System compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Complement System compounds?
Each Complement System product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Complement System compounds by activity or structure?
Yes. Filter the Complement System listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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