Immunology/Inflammation - SphK Supplier | High Purity

Prodotti popolari

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N,N-Dimethyl-D-erythro-sphingosine (PKC inhibitor)
CAS: 119567-63-4 Formula: C₂₀H₄₁NO₂ Peso molecolare: 327.5

≥98%

◐ .Su ordinazione · 8–12 settimane Oggetto #: N274922
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Nome IUPAC

(E,2S,3R)-2-(dimethylamino)octadec-4-ene-1,3-diol

SMILES

CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O

InChIKey
YRXOQXUDKDCXME-YIVRLKKSSA-N

InChI

1S/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(18-22)21(2)3/h16-17,19-20,22-23H,4-15,18H2,1-3H3/b17-16+/t19-,20+/m0/s1

Sinonimi
SR-01000946568-1 | CHEBI:78759 | N,N-Dimethyl-D-erythrosphingenine | NCGC00161359-01 | BSPBio_001420 | (2S,3R,4E)-2-(...
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SLM 6031434 cloridrato
CAS: 1897379-34-8 PubChem CID: 134812833 Formula: C₂₂H₃₀F₃N₅O₂.HCl Peso molecolare: 489.96

≥98%(HPLC)

◐ .Su ordinazione · 8–12 settimane Oggetto #: S288509
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(2S)-2-[3-[4-octoxy-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboximidamide;hydrochloride

SMILES

CCCCCCCCOC1=C(C=C(C=C1)C2=NOC(=N2)C3CCCN3C(=N)N)C(F)(F)F.Cl

InChIKey
YIGAQKBPLMSWOD-LMOVPXPDSA-N

InChI

1S/C22H30F3N5O2.ClH/c1-2-3-4-5-6-7-13-31-18-11-10-15(14-16(18)22(23,24)25)19-28-20(32-29-19)17-9-8-12-30(17)21(26)27;/h10-11,14,17H,2-9,12-13H2,1H3,(Hshow more

Sinonimi
(2S)-2-[3-[4-(ottilossi)-3-(trifluorometil)fenil]-1,2,4-ossadiazol-5-il]-1-pirrolidinecarbossimidammide cloridrato
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MP A08, Inhibitor of sphingosine kinase 1;Inhibitor of sphingosine kinase 2
CAS: 219832-49-2 Formula: C₂₇H₂₅N₃O₄S₂ Peso molecolare: 519.64

Moligand™ ? ≥97%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M288047
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4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide

SMILES

CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C=NC3=CC=CC=C3NS(=O)(=O)C4=CC=C(C=C4)C

InChIKey
FLDBNMYJUMAXDQ-UHFFFAOYSA-N

InChI

1S/C27H25N3O4S2/c1-20-11-15-23(16-12-20)35(31,32)29-25-8-4-3-7-22(25)19-28-26-9-5-6-10-27(26)30-36(33,34)24-17-13-21(2)14-18-24/h3-19,29-30H,1-2H3

Sinonimi
NSC 122314 | 4-Methyl-N-[2-[[[2-[[(4-methylphenyl)sulfonyl]amino]phenyl]imino]methyl]phenyl]benzenesulfonamide | MP-A08
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PF 543 cloridrato
CAS: 1706522-79-3 PubChem CID: 121230770 Formula: C₂₇H₃₁NO₄S•HCl Peso molecolare: 502.07

≥98%(HPLC)

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P286792
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[(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol;hydrochloride

SMILES

CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.Cl

InChIKey
WNKWAZFYPZMDGJ-VQIWEWKSSA-N

InChI

1S/C27H31NO4S.ClH/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29;/h2-4,7-12,14-16,25,29H,5-6,1show more

Sinonimi
(2R)-1-[[4-[[3-Metil-5-[(fenilsolfonil)metil]fenossi]metil]metil]-2- pirrolidinemetanolo cloridrato
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PF-543, Inhibitor of sphingosine kinase 1;Inhibitor of sphingosine kinase 2
CAS: 1415562-82-1 Formula: C₂₇H₃₁NO₄S Peso molecolare: 465.6

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P125702
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[(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol

SMILES

CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4

InChIKey
NPUXORBZRBIOMQ-RUZDIDTESA-N

InChI

1S/C27H31NO4S/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29/h2-4,7-12,14-16,25,29H,5-6,13,17-show more

Sinonimi
DTXSID3063386 | BDBM50041978 | (2R)-1-[[4-[[3-Methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2-pyrrol...
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ABC294640, Sphingosine kinase 2 inhibitor
CAS: 915385-81-8 Formula: C₂₃H₂₅ClN₂O Peso molecolare: 380.91

Solido Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A127517
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3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide

SMILES

C1C2CC3(CC1CC(C2)(C3)C(=O)NCC4=CC=NC=C4)C5=CC=C(C=C5)Cl

InChIKey
CAOTVXGYTWCKQE-UHFFFAOYSA-N

InChI

1S/C23H25ClN2O/c24-20-3-1-19(2-4-20)22-10-17-9-18(11-22)13-23(12-17,15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8,17-18H,9-15H2,(H,26,27)

Sinonimi
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide | ABC294640 | ABC-294640 | BA162479 | BDBM50393642 ...
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SKI II, Inhibitor of delta 4-desaturase; sphingolipid 1;Inhibitor of sphingosine kinase 1;Inhibitor of sphingosine kinase 2
CAS: 312636-16-1 PubChem CID: 753704 Formula: C₁₅H₁₁ClN₂OS Peso molecolare: 302.78

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: S129855
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4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]phenol

SMILES

C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl

InChIKey
ZFGXZJKLOFCECI-UHFFFAOYSA-N

InChI

1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)

Sinonimi
CCG-265019 | HMS3413G03 | SKI II | Ski ii (sphk-i2) | HMS3650M12 | NCGC00092309-01 | SKI 2 | BDBM50312869 | HMS3677G0...
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SKI-I
CAS: 306301-68-8 PubChem CID: 137269090 Formula: C25H18N4O2 Peso molecolare: 406.44

≥90%

◐ .Su ordinazione · 8–12 settimane Oggetto #: S275155
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N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-5-naphthalen-2-ylpyrazolidine-3-carboxamide

SMILES

C1C(NNC1C(=O)NN=CC2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4

InChIKey
LMCALHGHWCFFHD-CVKSISIWSA-N

InChI

1S/C25H22N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-13,15,22-23,27-28,30H,14H2,(H,29,show more

Sinonimi
5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylicacid2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
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omega-biotinyl D-erythro-sphingosine
CAS: 752987-57-8 PubChem CID: 46891739 Formula: C₂₈H₅₂N₄O₄S Peso molecolare: 540.802

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: O130651
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5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[(E,16R,17S)-17-amino-16,18-dihydroxyoctadec-14-enyl]pentanamide

SMILES

C1C2C(C(S1)CCCCC(=O)NCCCCCCCCCCCCCC=CC(C(CO)N)O)NC(=O)N2

InChIKey
NYQVYZZGZCNEMF-RPRIXWAOSA-N

InChI

1S/C28H52N4O4S/c29-22(20-33)24(34)16-12-10-8-6-4-2-1-3-5-7-9-11-15-19-30-26(35)18-14-13-17-25-27-23(21-37-25)31-28(36)32-27/h12,16,22-25,27,33-34H,1-1show more
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ABC294640, Sphingosine kinase 2 inhibitor
CAS: 915385-81-8 Formula: C₂₃H₂₅ClN₂O Peso molecolare: 380.91

Moligand™ ? 10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A426910
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3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide

SMILES

C1C2CC3(CC1CC(C2)(C3)C(=O)NCC4=CC=NC=C4)C5=CC=C(C=C5)Cl

InChIKey
CAOTVXGYTWCKQE-UHFFFAOYSA-N

InChI

1S/C23H25ClN2O/c24-20-3-1-19(2-4-20)22-10-17-9-18(11-22)13-23(12-17,15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8,17-18H,9-15H2,(H,26,27)

Sinonimi
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide | ABC294640 | ABC-294640 | BA162479 | BDBM50393642 ...
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CAY10621 (SKI 5C)
CAS: 120005-55-2 Formula: C₂₆H₄₅NO₄ Peso molecolare: 435.65

≥98%

◐ .Su ordinazione · 8–12 settimane Oggetto #: C276256
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tert-butyl (4S)-4-hexadec-2-ynoyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

SMILES

CCCCCCCCCCCCCC#CC(=O)C1COC(N1C(=O)OC(C)(C)C)(C)C

InChIKey
YGBSGZPIDCXNEH-QFIPXVFZSA-N

InChI

1S/C26H45NO4/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(28)22-21-30-26(5,6)27(22)24(29)31-25(2,3)4/h22H,7-18,21H2,1-6H3/t22-/m0/s1

Sinonimi
tert-Butyl(4S)-4-hexadec-2-ynoyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
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Defensamide (MHP)
CAS: 1104874-94-3 Formula: C₁₆H₂₃NO₄ Peso molecolare: 293.36

10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D420603
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methyl (2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoate

SMILES

CCCCCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)OC

InChIKey
GBTVWZMJUZJPBU-AWEZNQCLSA-N

InChI

1S/C16H23NO4/c1-3-4-5-6-15(19)17-14(16(20)21-2)11-12-7-9-13(18)10-8-12/h7-10,14,18H,3-6,11H2,1-2H3,(H,17,19)/t14-/m0/s1

Sinonimi
ZB1539 | (S)-Methyl 2-(hexanamido)-3-(4-hydroxyphenyl)propanoate | (S)-methyl 2-hexanamido-3-(4-hydroxyphenyl)propano...

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Domande frequenti

What can I find under SphK?

This listing collects compounds associated with SphK within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.

What should I consider when picking a compound for SphK?

Consider the reported potency of each SphK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.

What quality information is provided for SphK compounds?

Each SphK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search SphK compounds by activity or structure?

Yes. Filter the SphK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].