FLAP

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36 prodotti

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  1. MK-0591
    CAS: 136668-42-3 Formula: C34H35ClN2O3S Peso molecolare: 587.17
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M125295
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    3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid
    SMILES
    CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O
    InChIKey
    NZOONKHCNQFYCI-UHFFFAOYSA-N
    InChI
    1S/C34H35ClN2O3S/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39/h6-show more
    Sinonimi
    SB19076 | MK 0591 | 3-(tert-Butylthio)-1-(p-chlorobenzyl)-alpha,alpha-dimethyl-5-(2-quinolylmethoxy)indole-2-propioni...
  2. MK-591 sodium
    CAS: 147030-01-1 Formula: C34H34ClN2NaO3S Peso molecolare: 609.15
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: M125732
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    sodium;3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoate
    SMILES
    CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)[O-].[Na+]
    InChIKey
    YPURUCMVRRNPHJ-UHFFFAOYSA-M
    InChI
    1S/C34H35ClN2O3S.Na/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39;show more
    Sinonimi
    321US0I5R6 | sodium 3-[1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)-3-tert-butylsulfanyl-indol-2-yl]-2,2-dimet...
  3. MK886, Antagonist of Peroxisome proliferator-activated receptor-α
    CAS: 118414-82-7 Formula: C27H34ClNO2S Peso molecolare: 472.08
    Solido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M275434
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    3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid
    SMILES
    CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl
    InChIKey
    QAOAOVKBIIKRNL-UHFFFAOYSA-N
    InChI
    1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)
    Sinonimi
    1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-?,?-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid | 3-...
  4. AM679
    CAS: 1206880-66-1 PubChem CID: 44627267 Formula: C40H44N4O5S Peso molecolare: 692.87
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: A127302
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    3-[5-[[(2S)-1-acetyl-2,3-dihydroindol-2-yl]methoxy]-3-tert-butylsulfanyl-1-[[4-(5-methoxypyrimidin-2-yl)phenyl]methyl]indol-2-yl]-2,2-dimethylpropanoishow more
    SMILES
    CC(=O)N1C(CC2=CC=CC=C21)COC3=CC4=C(C=C3)N(C(=C4SC(C)(C)C)CC(C)(C)C(=O)O)CC5=CC=C(C=C5)C6=NC=C(C=N6)OC
    InChIKey
    VYXWHVDEWWHDLH-LJAQVGFWSA-N
    InChI
    1S/C40H44N4O5S/c1-25(45)44-29(18-28-10-8-9-11-33(28)44)24-49-30-16-17-34-32(19-30)36(50-39(2,3)4)35(20-40(5,6)38(46)47)43(34)23-26-12-14-27(15-13-26)3show more
    Sinonimi
    (S)-3-(5-((1-acetylindolin-2-yl)methoxy)-3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-1H-indol-2-yl)-2,2-...
  5. LNT 1
    CAS: 824983-91-7 Formula: C15H12N2O5S Peso molecolare: 332.33
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: L288189
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    1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione
    SMILES
    C1C(OC2=CC=CC=C2O1)CN3C4=C(C(=O)N(C3=O)O)SC=C4
    InChIKey
    MXQGCMQXTPTJJT-UHFFFAOYSA-N
    InChI
    1S/C15H12N2O5S/c18-14-13-10(5-6-23-13)16(15(19)17(14)20)7-9-8-21-11-3-1-2-4-12(11)22-9/h1-6,9,20H,7-8H2
    Sinonimi
    1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione
  6. BAY-X 1005, 5-lipoxygenase activating protein inhibitor
    CAS: 128253-31-6 Formula: C23H23NO3 Peso molecolare: 361.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: B288165
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    (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid
    SMILES
    C1CCC(C1)C(C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O
    InChIKey
    ZEYYDOLCHFETHQ-JOCHJYFZSA-N
    InChI
    1S/C23H23NO3/c25-23(26)22(17-6-1-2-7-17)18-10-13-20(14-11-18)27-15-19-12-9-16-5-3-4-8-21(16)24-19/h3-5,8-14,17,22H,1-2,6-7,15H2,(H,25,26)/t22-/m1/s1
    Sinonimi
    (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid | (R)-Cyclopentyl-[4-(quinolin-2-ylmethoxy)-phenyl]-...
  7. FEN1-IN-4
    CAS: 1995893-58-7 Formula: C12H12N2O3 Peso molecolare: 232.24
    10mM in DMSO
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: F422425
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    1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4-dione
    SMILES
    C1CC1CN2C3=CC=CC=C3C(=O)N(C2=O)O
    InChIKey
    JAFLWTUYSKADJS-UHFFFAOYSA-N
    InChI
    1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2
    Sinonimi
    FEN1 Inhibitor C2 | JUN935872,​4(1H,​3H)​-​Quinazolinedione,1-​(cyclopropylmethyl)​-​3-​hydroxy-
  8. FEN1-IN-4
    CAS: 1995893-58-7 Formula: C12H12N2O3 Peso molecolare: 232.24
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: F412918
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    1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4-dione
    SMILES
    C1CC1CN2C3=CC=CC=C3C(=O)N(C2=O)O
    InChIKey
    JAFLWTUYSKADJS-UHFFFAOYSA-N
    InChI
    1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2
    Sinonimi
    FEN1 Inhibitor C2 | JUN93587
  9. MK886, Antagonist of Peroxisome proliferator-activated receptor-α
    CAS: 118414-82-7 Formula: C27H34ClNO2S Peso molecolare: 472.08
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M420810
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    3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid
    SMILES
    CC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl
    InChIKey
    QAOAOVKBIIKRNL-UHFFFAOYSA-N
    InChI
    1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)
    Sinonimi
    1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-?,?-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid | 3-...
  10. Diflapolin, Inhibitor of epoxide hydrolase 2
    CAS: 724453-98-9 PubChem CID: 4560409 Formula: C22H17Cl2N3O2S Peso molecolare: 458.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D609883
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    1-[4-(1,3-benzothiazol-2-ylmethoxy)-2-methylphenyl]-3-(3,4-dichlorophenyl)urea
    SMILES
    CC1=C(C=CC(=C1)OCC2=NC3=CC=CC=C3S2)NC(=O)NC4=CC(=C(C=C4)Cl)Cl
    InChIKey
    FGXLEECGXSDIMM-UHFFFAOYSA-N
    InChI
    1S/C22H17Cl2N3O2S/c1-13-10-15(29-12-21-26-19-4-2-3-5-20(19)30-21)7-9-18(13)27-22(28)25-14-6-8-16(23)17(24)11-14/h2-11H,12H2,1H3,(H2,25,27,28)
  11. Fiboflapon sodium, 5-lipoxygenase activating protein inhibitor
    CAS: 1196070-26-4 Numero EC: 689-173-7 PubChem CID: 44473150 Formula: C38H42N3NaO4S Peso molecolare: 659.81
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: F647997
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    sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate
    SMILES
    CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)[O-])SC(C)(C)C.[Na+]
    InChIKey
    NOJNFULGOQGBKB-UHFFFAOYSA-M
    InChI
    1S/C38H43N3O4S.Na/c1-8-44-34-18-14-28(22-40-34)27-12-10-26(11-13-27)23-41-32-17-16-30(45-24-29-15-9-25(2)21-39-29)19-31(32)35(46-37(3,4)5)33(41)20-38(show more
    Sinonimi
    GSK2190915 sodium salt | SCHEMBL1254527 | sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5...
  12. AM103
    CAS: 1147872-22-7 PubChem CID: 129010507 Formula: C36H38N3NaO4S Peso molecolare: 631.76
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: A647147
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    SMILES
    CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=CC=CC=N3)CC4=CC=C(C=C4)C5=CN=C(C=C5)OC)CC(C)(C)C(=O)O.[Na]
    InChIKey
    VANSVYMYESBUFV-UHFFFAOYSA-N
    InChI
    1S/C36H39N3O4S.Na/c1-35(2,3)44-33-29-19-28(43-23-27-9-7-8-18-37-27)15-16-30(29)39(31(33)20-36(4,5)34(40)41)22-24-10-12-25(13-11-24)26-14-17-32(42-6)38show more
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Domande frequenti

Which compounds are listed for FLAP?
Compounds associated with FLAP are grouped here under the Immunology/Inflammation classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does FLAP sit within Immunology/Inflammation?
FLAP is one target listing within the Immunology/Inflammation classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from FLAP?
For compounds listed under FLAP, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for FLAP?
Browse the parent Immunology/Inflammation listing to reach targets neighbouring FLAP, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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