2,2'-Dithiobis(5-nitropyridine)(DTNP) - ≥96%, used for as cysteine-activating reagent to study the NMR of G protein-coupled receptors; in the deprotection assays for protected selenocysteine-containing peptides; for deprotecting p-methoxybenzyl groups and

CAS: 2127-10-8 Cat. No.: D579178 Fórmula: C10H6N4O4S2 Peso molecular: 310.31 Beilstein Registry Number: 305413 Número CE: 218-344-7
Disponível para encomenda
GRADE & PURITY ≥96%
Synonyms
DTNP | InChI=1/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6 | Pyridine,2'-dithiobis[5-nitro- | NSC677436 | NSC-677436 | 2,2'-Dithiobis(5-nitropyridine), 96% | NSC 149336 | 2,2'-disulfanediylbis(5-nitropyridine) | 5,5'-Dinitro-
Storage
Room temperature,Desiccated
Shipped In
Normal
★
Size
Alemanha (EU)
USA*
Price
Qty
0.5g
D579178-0.5g
—
3 Em stock
25,95€
250mg
D579178-250mg
Sob encomenda · 8–12 semanas
17,27€
1g
D579178-1g
—
1 Em stock
39,83€
5g
D579178-5g
Sob encomenda · 8–12 semanas
100,57€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.

Specifications

Sinónimos
DTNP | InChI=1/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6 | Pyridine,2'-dithiobis[5-nitro- | NSC677436 | NSC-677436 | 2,2'-Dithiobis(5-nitropyridine), 96% | NSC 149336 | 2,2'-disulfanediylbis(5-nitropyridine) | 5,5'-Dinitro-
Especificações e pureza
≥96%
Aplicação
as cysteine-activating reagent to study the NMR of G protein-coupled receptors; in the deprotection assays for protected selenocysteine-containing peptides; for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cystein
Condições de armazenamento de armazenamento
Room temperature,Desiccated
Enviado em
Normal
Pureza
≥96%
Nomes e identificadores
Pubchem Sid488182250
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182250
Sorrisos canónicosC1=CC(=NC=C1[N+](=O)[O-])SSC2=NC=C(C=C2)[N+](=O)[O-]
IUPAC Name5-nitro-2-[(5-nitropyridin-2-yl)disulfanyl]pyridine
InChIKeyROUFCTKIILEETD-UHFFFAOYSA-N
INCHI1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H
SMILES isoméricas C1=CC(=NC=C1[N+](=O)[O-])SSC2=NC=C(C=C2)[N+](=O)[O-]
WGK Alemanha 3
RTECS UT2964000
Peso molecular 310.31
Beilstein 305413
Reaxy-Rn 305413
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=305413&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic 1,3-dipolar compounds
ClasseAllyl-type 1,3-dipolar organic compounds
SubclassOrganic nitro compounds
Intermediate Tree Nodes C-nitro compounds
Direct ParentNitroaromatic compounds
Alternative Parents Pyridines and derivatives  Heteroaromatic compounds  Organic disulfides  Sulfenyl compounds  Propargyl-type 1,3-dipolar organic compounds  Organic oxoazanium compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Nitroaromatic compound - Pyridine - Heteroaromatic compound - Organic disulfide - Organic oxoazanium - Sulfenyl compound - Propargyl-type 1,3-dipolar organic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as nitroaromatic compounds. These are c-nitro compounds where the nitro group is C-substituted with an aromatic group.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
TRPV1 Tclin Vanilloid receptor (8273 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPV4 Tchem Transient receptor potential cation channel subfamily V member 4 (774 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 (542 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 (348 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDataItem
C2627409Certificate of AnalysisFeb 27, 2026 D579178
C2627410Certificate of AnalysisFeb 27, 2026 D579178
C2627411Certificate of AnalysisFeb 27, 2026 D579178
H2603064Certificate of AnalysisFeb 27, 2026 D579178
F2301563Certificate of AnalysisJun 10, 2023 D579178
F2301573Certificate of AnalysisJun 10, 2023 D579178
F2302157Certificate of AnalysisJun 09, 2023 D579178
F2302159Certificate of AnalysisJun 09, 2023 D579178
Propriedades químicas e físicas
Ponto de fusão (°C)155°C
Peso molecular310.300 g/mol
XLogP32.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass309.983 Da
Monoisotopic Mass309.983 Da
Topological Polar Surface Area168.000 Ų
Heavy Atom Count20
Formal Charge0
Complexity328.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referências
1. Kefan Ouyang, Qian Chen, Hexiang Xie, Qin Zhang, Liling Tao, Hua Xiong, Yulan Du, Jiangang Yan, Xinliang Mao, Qiang Zhao.  (2023)  Arthrospira cell residue valorization: A study on protein hydrolysate production by limited enzymatic hydrolysis.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2023.103264]
2. Lyulin Hu, Sijie Ren, Qing Shen, Xingqian Ye, Jianchu Chen, Jiangang Ling.  (2018)  Protein oxidation and proteolysis during roasting and in vitro digestion of fish (Acipenser gueldenstaedtii).  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  98  (14): (5344-5351).  [PMID:29656426] [10.1002/jsfa.9075]
3. Lyulin Hu, Sijie Ren, Qing Shen, Jianchu Chen, Xingqian Ye, Jiangang Ling.  (2017)  Proteomic study of the effect of different cooking methods on protein oxidation in fish fillets.  RSC Advances,  7  (44): (27496-27505).  [PMID:] [10.1039/C7RA03408C]
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

What is the purity of this product?
This product is supplied at ≥96% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store in a cool place, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships under standard ambient conditions. No temperature-controlled packaging is required.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2127-10-8, the molecular formula is C10H6N4O4S2, and the molecular weight is 310.31 g/mol. InChIKey ROUFCTKIILEETD-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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