11β-HSD

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  1. Emodin
    CAS: 518-82-1 EC Number: 208-258-8 Formula: C15H10O5 Molecular Weight: 270.24
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥96%(HPLC)
    ● In Stock — US Item #: E106693
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    IUPAC Name
    1,3,8-trihydroxy-6-methylanthracene-9,10-dione
    SMILES
    CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O
    InChIKey
    RHMXXJGYXNZAPX-UHFFFAOYSA-N
    InChI
    1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
    Synonyms
    EMO | Frangula emodin | MEGxp0_000460 | 1,3,8-Trihydroxy-6-methylanthraquinone | C.I. Natural Yellow 14 | Lopac-E-788...
  2. Emodin
    CAS: 518-82-1 EC Number: 208-258-8 Formula: C15H10O5 Molecular Weight: 270.24
    ● In Stock — US Item #: E106692
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    Technical Identifiers
    IUPAC Name
    1,3,8-trihydroxy-6-methylanthracene-9,10-dione
    SMILES
    CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O
    InChIKey
    RHMXXJGYXNZAPX-UHFFFAOYSA-N
    InChI
    1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
    Synonyms
    EMO | Frangula emodin | MEGxp0_000460 | 1,3,8-Trihydroxy-6-methylanthraquinone | C.I. Natural Yellow 14 | Lopac-E-788...
  3. 4-(Trifluoromethyl)benzophenone
    CAS: 728-86-9 PubChem CID: 69767 Formula: C14H9F3O Molecular Weight: 250.22
    ● In Stock — US Item #: T354141
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    IUPAC Name
    phenyl-[4-(trifluoromethyl)phenyl]methanone
    SMILES
    C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C(F)(F)F
    InChIKey
    OHTYZZYAMUVKQS-UHFFFAOYSA-N
    InChI
    1S/C14H9F3O/c15-14(16,17)12-8-6-11(7-9-12)13(18)10-4-2-1-3-5-10/h1-9H
    Synonyms
    4-(Trifluoromethyl)benzophenone | 4'-Trifluoromethylbenzophenone | 4-Trifluoromethylbenzophenone | FT-0616918 | InChI...
  4. 11α-Hydroxy Progesterone
    CAS: 80-75-1 EC Number: 201-306-9 Formula: C21H30O3 Molecular Weight: 330.46
    Solid ≥98%
    ● In Stock — US Item #: H137696
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    IUPAC Name
    (8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    SMILES
    CC(=O)C1CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C
    InChIKey
    BFZHCUBIASXHPK-QJSKAATBSA-N
    InChI
    1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18+,19+,20-,21+/m0/sshow more
    Synonyms
    (8S,10R,11R,13S,17S)-17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopent...
  5. Emodin-d4
    CAS: 132796-52-2 Formula: C15H6D4O5 Molecular Weight: 274.26
    ◐ .Made to order · 8–12 wks Item #: E345246
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    IUPAC Name
    1-deuterio-4,5,7-trihydroxy-2-(trideuteriomethyl)anthracene-9,10-dione
    SMILES
    CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O
    InChIKey
    RHMXXJGYXNZAPX-MZCSYVLQSA-N
    InChI
    1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3/i1D3,2D
    Synonyms
    1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione-d4 | 1,6,8-Trihydroxy-3-methylanthraquinone-d4 | 4,5,7-Trihydroxy-2-me...
  6. Tetrahydro-11-dehydrocorticosterone
    CAS: 566-03-0 PubChem CID: 223684 Formula: C21H32O4 Molecular Weight: 348.48
    ● In Stock — US Item #: T353078
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    Technical Identifiers
    IUPAC Name
    (3R,5R,8S,9S,10S,13S,14S,17S)-3-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11show more
    SMILES
    CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4C(=O)CO)C)O
    InChIKey
    XWYBFXIUISNTQG-RHBMFIQRSA-N
    InChI
    1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13-,14+,15+,16-,19-,20+,show more
    Synonyms
    (3R,5R,8S,9S,10S,13S,14S,17S)-3-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradec...
  7. 4-Androsten-11β-ol-3,17-dione
    CAS: 382-44-5 Formula: C19H26O3 Molecular Weight: 302.41
    ● In Stock — US Item #: A118720
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    Technical Identifiers
    IUPAC Name
    (8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
    SMILES
    CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4=O)C)O
    InChIKey
    WSCUHXPGYUMQEX-KCZNZURUSA-N
    InChI
    1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
    Synonyms
    Androst-4-en-3,17-dione, 11beta-hydroxy- | (2E,4E)-2,4-Heptadien-1-ol | NCGC00485120-01 | (E,E)-2,4-Dodecadien-1-al |...
  8. BVT 2733
    CAS: 376640-41-4 Formula: C17H21ClN4O3S2 Molecular Weight: 428.96
    ● In Stock — US Item #: B412243
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    Technical Identifiers
    IUPAC Name
    3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide
    SMILES
    CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=NC(=CS2)CC(=O)N3CCN(CC3)C
    InChIKey
    YDPRNGAPPNPYQQ-UHFFFAOYSA-N
    InChI
    1S/C17H21ClN4O3S2/c1-12-14(18)4-3-5-15(12)27(24,25)20-17-19-13(11-26-17)10-16(23)22-8-6-21(2)7-9-22/h3-5,11H,6-10H2,1-2H3,(H,19,20)
    Synonyms
    BVT.2733 | MFCD13152134 | Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl- ...
  9. BVT 2733
    CAS: 376640-41-4 EC Number: 808-805-6 Formula: C17H21ClN4O3S2 Molecular Weight: 428.96
    10mM in DMSO
    ● In Stock — US Item #: B423696
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    Technical Identifiers
    IUPAC Name
    3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide
    SMILES
    CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=NC(=CS2)CC(=O)N3CCN(CC3)C
    InChIKey
    YDPRNGAPPNPYQQ-UHFFFAOYSA-N
    InChI
    1S/C17H21ClN4O3S2/c1-12-14(18)4-3-5-15(12)27(24,25)20-17-19-13(11-26-17)10-16(23)22-8-6-21(2)7-9-22/h3-5,11H,6-10H2,1-2H3,(H,19,20)
    Synonyms
    376640-41-4|BVT 2733|BVT-2733|3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfo...
  10. BVT-14225
    CAS: 376638-65-2 Formula: C16H20ClN3O3S2 Molecular Weight: 401.9
    ◐ .Made to order · 8–12 wks Item #: B412260
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    Technical Identifiers
    IUPAC Name
    2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide
    SMILES
    CCN(CC)C(=O)CC1=CSC(=N1)NS(=O)(=O)C2=C(C(=CC=C2)Cl)C
    InChIKey
    PNFMZAHWOASGJC-UHFFFAOYSA-N
    InChI
    1S/C16H20ClN3O3S2/c1-4-20(5-2)15(21)9-12-10-24-16(18-12)19-25(22,23)14-8-6-7-13(17)11(14)3/h6-8,10H,4-5,9H2,1-3H3,(H,18,19)
  11. Carbenoxolone Disodium
    CAS: 7421-40-1 PubChem CID: 636402 Formula: C34H48Na2O7 Molecular Weight: 614.72
    ● In Stock — US Item #: C134840
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    Technical Identifiers
    IUPAC Name
    disodium;(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxylatopropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-doshow more
    SMILES
    CC1(C2CCC3(C(C2(CCC1OC(=O)CCC(=O)[O-])C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)[O-])C)C)C)C.[Na+].[Na+]
    InChIKey
    BQENDLAVTKRQMS-SBBGFIFASA-L
    InChI
    1S/C34H50O7.2Na/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6;;/h1show more
    Synonyms
    UNII-F1MP7242Z5 | CARBENOXOLONE SODIUM | CARBENOXOLONE SODIUM [WHO-DD] | Prestwick_19 | OLEAN-12-EN-29-OIC ACID, 3-(3...
  12. Equisetin
    CAS: 57749-43-6 Formula: C22H31NO4 Molecular Weight: 373.49
    ◐ .Made to order · 8–12 wks Item #: E329522
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    Technical Identifiers
    IUPAC Name
    (3E,5S)-3-[[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(E)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-meshow more
    SMILES
    CC=CC1C=CC2CC(CCC2C1(C)C(=C3C(=O)C(N(C3=O)C)CO)O)C
    InChIKey
    QNQBPPQLRODXET-AIMHRHHOSA-N
    InChI
    1S/C22H31NO4/c1-5-6-15-9-8-14-11-13(2)7-10-16(14)22(15,3)20(26)18-19(25)17(12-24)23(4)21(18)27/h5-6,8-9,13-17,24,26H,7,10-12H2,1-4H3/b6-5+,20-18+/t13-show more
    Synonyms
    V56ZMM5VMZ | Equisetin | HY-N6711 | DTXSID001017630 | QNQBPPQLRODXET-AIMHRHHOSA-N | 2,4-Pyrrolidinedione, 5-(hydroxym...
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Frequently Asked Questions

Which compounds are listed for 11β-HSD?
Compounds associated with 11β-HSD are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does 11β-HSD sit within Metabolic Enzyme/Protease?
11β-HSD is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from 11β-HSD?
For compounds listed under 11β-HSD, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for 11β-HSD?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring 11β-HSD, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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