Ligands for E3 Ligase

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  1. 2-(2,6-Dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione
    CAS: 40313-92-6 Formula: C14H12N2O4 Molecular Weight: 272.26
    Out of Stock Item #: D1238302
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    Technical Identifiers
    IUPAC Name
    2-(2,6-dioxopiperidin-3-yl)-5-methylisoindole-1,3-dione
    SMILES
    CC1=CC2=C(C=C1)C(=O)N(C2=O)C3CCC(=O)NC3=O
    InChIKey
    FIRKPGPRAMCBHV-UHFFFAOYSA-N
    InChI
    1S/C14H12N2O4/c1-7-2-3-8-9(6-7)14(20)16(13(8)19)10-4-5-11(17)15-12(10)18/h2-3,6,10H,4-5H2,1H3,(H,15,17,18)
  2. (4R,5S)-Nutlin carboxylic acid
    CAS: 2306390-08-7 PubChem CID: 138911380
    Out of Stock Item #: R1449802
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    Technical Identifiers
    IUPAC Name
    2-[4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetic acid
    SMILES
    CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCN(C(=O)C3)CC(=O)O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
    InChIKey
    CYFZSMNCDNFMOG-IHLOFXLRSA-N
    InChI
    1S/C32H32Cl2N4O6/c1-19(2)44-26-16-24(43-3)12-13-25(26)31-35-29(20-4-8-22(33)9-5-20)30(21-6-10-23(34)11-7-21)38(31)32(42)37-15-14-36(18-28(40)41)27(39)show more
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