5-Methyl-2-thiouridine - ≥98% , CAS No.32738-09-3

CAS: 32738-09-3 Cat. No.: M350280 Fórmula: C₁₀H₁₄N₂O₅S Peso molecular: 274.29

GRADE & PURITY ≥98%

Synonyms

Y9TK5VEJ8P | F89426 | s2t | 5-Methyl-2-thiouridine | UNII-Y9TK5VEJ8P | 2-Thioribothymidine | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one | Methyl thiouridine | PS-18886 | 1-[(2R,3R,4S,5R)-3,4-dihydr

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

5-Methyl-2-thiouridine (m5s2U) is a modified base found in the tRNA of certain extreme thermophiles. 5-Methyl-2-thiouridine may be used to study the physical chemical properties that confer high stability to tRNA and other nucleic acid structures.

Specifications

Sinónimos

Y9TK5VEJ8P | F89426 | s2t | 5-Methyl-2-thiouridine | UNII-Y9TK5VEJ8P | 2-Thioribothymidine | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one | Methyl thiouridine | PS-18886 | 1-[(2R,3R,4S,5R)-3,4-dihydr

Especificações e pureza

≥98%

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

• Pubchem Sid: 504764333
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764333
• Sorrisos canónicos: CC1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O
• IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
• InChIKey: SNNBPMAXGYBMHM-JXOAFFINSA-N
• INCHI: 1S/C10H14N2O5S/c1-4-2-12(10(18)11-8(4)16)9-7(15)6(14)5(3-13)17-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,18)/t5-,6-,7-,9-/m1/s1
• SMILES isoméricas: CC1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
• Peso molecular: 274.29
• Reaxy-Rn: 14617460
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14617460&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Classe Pyrimidine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Classe: Pyrimidine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrimidine nucleosides
• Alternative Parents: Glycosylamines Pentoses Pyrimidones Pyrimidinethiones 2-Thiopyrimidines Hydropyrimidines Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Thioureas Secondary alcohols Lactams Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Primary alcohols
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Pyrimidinethione - Pyrimidone - 2-thiopyrimidine - Thiopyrimidine - Hydropyrimidine - Pyrimidine - Monosaccharide - Vinylogous amide - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Thiourea - Lactam - Oxacycle - Azacycle - Organoheterocyclic compound - Alcohol - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary alcohol - Organic nitrogen compound - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: thiouridine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Ponto de fusão (°C): 216-219° C
• Peso molecular: 274.300 g/mol
• XLogP3: -1.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 274.062 Da
• Monoisotopic Mass: 274.062 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 413.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1