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224,000+ produtos de pesquisa · Triple ISO certified · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque

Início
Por alvo / caminho / doença
Por vias de sinalização
Epigenética
Domínio leitor epigenético
A-485 - Moligand™, 10 mM in DMSO , CAS No.1889279-16-6

A-485 - Moligand™, 10 mM in DMSO , CAS No.1889279-16-6

Name: A-485 - Moligand™, 10 mM in DMSO , CAS No.1889279-16-6
SKU: A1493948
Availability: InStock

CAS: 1889279-16-6 Cat. No.: A1493948 Fórmula: C₂₅H₂₄F₄N₄O₅ Peso molecular: 536.48

2 Citations COA

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A-485 - Moligand™, 10 mM in DMSO CAS No(1889279-16-6) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY Moligand™ ? 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Certificados（CoA,COO,BSE/TSE e Mapa de Análise) FAQs e artigos Citations of This Product Referências Calculadoras de soluções Revisões

🧪

Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC 50 s of 9.8?nM and 2.6?nM for p300 and CBP histone acetyltransferase (HAT), respectively.

Specifications

Especificações e pureza

Moligand™, 10 mM in DMSO

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

INHIBITOR

Nomes e identificadores

SMILES isoméricas	C[C@@H](C(F)(F)F)N(CC1=CC=C(C=C1)F)C(=O)CN2C(=O)[C@]3(CCC4=C3C=CC(=C4)NC(=O)NC)OC2=O
Peso molecular	536.48

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados（CoA,COO,BSE/TSE e Mapa de Análise)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

FAQs e artigos

If the DNA Sequence Remains Unchanged, Why Does Gene Expression Change? Core Mechanisms and Research Methods of Epigenetic Regulation

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

DNA Epigenetics gene expression

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

Referências

1. Junhui Lv, Zhinang Yin, Conghui Li, Honglin Wen, Jian Ni, Peiyuan Yang, Zemin Song, Ying Xiang, Honghong Wang, Rui Lu, Li Huang, Ying Zhou, Hai-Bing Zhou, Ruijing Xiao, Pingping Fang, Kaiwei Liang. (2025) KAT6A chimeras form a self-reinforcing epigenetic module with NURF and MLL/COMPASS to sustain AML. GENOME BIOLOGY, [PMID:40830799] [10.1186/s13059-025-03743-y]
2. Zongxin Zhu, Ximiao Chen, Hanwen Zhang, Ronghui Miao, Huiling Yu, Shiying Zhao, Youli Zhang, Tanxin Yu, Di Zhang, Yifei Zhou, Xiaolei Zhang, Wei Zhang. (2026) Lactate-driven H3K27 lactylation promotes Olig2-dependent remyelination and motor recovery after spinal cord injury. NEUROPHARMACOLOGY, [PMID:41525841] [10.1016/j.neuropharm.2026.110832]

Calculadoras de soluções

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Revisões

📚 Citations by Application

Drug / compound screening1

Other applications1

View all 2 citations →

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

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