A 804598 - Moligand™, ≥98% , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7

CAS: 1125758-85-1 Cat. No.: A287786 Fórmula: C19H17N5 Peso molecular: 315.37 Número CE: 802-550-4
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Alemanha (EU)
USA*
Price
Qty
5mg
A287786-5mg
Sob encomenda · 8–12 semanas
124,00€
10mg
A287786-10mg
—
5 Em stock
190,82€
50mg
A287786-50mg
—
3 Em stock
594,31€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Especificações e pureza
Moligand™, ≥98%
Mecanismos bioquímicos e fisiológicos
Potent, competitive P2X7receptor antagonist (IC50values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7receptors respectively). Selective for P2X7receptors (IC50> 5-10μM for a wide array of cell surface receptors and ion channels). Binds with high
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Grau
Moligand™
Tipo de ação
ANTAGONIST
Mecanismo de ação
Antagonist of P2X7
Pureza
≥98%
Nomes e identificadores
Pubchem Sid504771149
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504771149
Sorrisos canónicosCC(C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
IUPAC Name1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
InChIKeyPQYCRDPLPKGSME-AWEZNQCLSA-N
INCHI1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
SMILES isoméricas C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
Peso molecular 315.37
Reaxy-Rn 31636225
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31636225&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
P2RX7 Tchem P2X purinoceptor 7 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDataItem
B2218322Certificate of AnalysisDec 17, 2024 A287786
B2218335Certificate of AnalysisDec 17, 2024 A287786
Propriedades químicas e físicas
SolubilidadeSolvent:DMSO, Max Conc. mg/mL: 31.54, Max Conc. mM: 100
Peso molecular315.400 g/mol
XLogP34.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass315.148 Da
Monoisotopic Mass315.148 Da
Topological Polar Surface Area73.100 Ų
Heavy Atom Count24
Formal Charge0
Complexity473.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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