Ac-IEPD-CHO - ≥95% , CAS No.A276505

CAS: A276505 Cat. No.: A276505 Fórmula: C₂₂H₃₄N₄O₉ Peso molecular: 498.53

GRADE & PURITY ≥95%

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

Reversible inhibitor of Granzyme B and caspase B. The reversible inhibitor of Granzyme B can also inhibit caspase B. Granzyme B is a protease that participates in the induction of rapid target cell death through cytotoxic lymphocytes. 

Product description：

The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Specifications

Especificações e pureza

≥95%

Mecanismos bioquímicos e fisiológicos

Reversible granzyme B (K i = 80 nM) and caspase-8 inhibitor. Also inhibits caspase-7 (K i = 550 nM) and apoptosis in multiple biological systems. Main target Granzyme B The product does not compete with ATP. Reversibility: Yes Cell permeability: No

Condições de armazenamento de armazenamento

Store at -20°C,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nomes e identificadores

Peso molecular

498.53

Propriedades químicas e físicas

• Solubilidade: Soluble in DMSO