Acetyl Spiramycin - Potency ≥ 1200u/mg (on a dry basis) , CAS No.24916-51-6

CAS: 24916-51-6 Cat. No.: A353881 Fórmula: C₄₅H₇₆N₂O₁₅ Peso molecular: 885.1 PubChem CID: 49787020

GRADE & PURITY Potency ≥ 1200u/mg (on a dry basis)

Synonyms

Acetylspiramycin (TN) | Acetylspiramycin (ASPM) | SPIRAMYCIN 2 [WHO-DD] | [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Acetyl Spiramycin is an antibiotic substance classified in the erythromycin-carbomycin group.

Specifications

Sinónimos

Acetylspiramycin (TN) | Acetylspiramycin (ASPM) | SPIRAMYCIN 2 [WHO-DD] | [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]

Especificações e pureza

Potency ≥ 1200u/mg (on a dry basis)

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

• Pubchem Sid: 504770927
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504770927
• Sorrisos canónicos: CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)OC(=O)C)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C
• IUPAC Name: [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] acetate
• InChIKey: ZPCCSZFPOXBNDL-ZSTSFXQOSA-N
• INCHI: 1S/C45H76N2O15/c1-25-22-31(20-21-48)41(62-44-39(51)38(47(10)11)40(28(4)58-44)61-37-24-45(7,53)43(52)29(5)57-37)42(54-12)34(59-30(6)49)23-35(50)55-26(2)16-14-13-15-17-33(25)60-36-19-18-32(46(8)9)27(3)56-36/h13-15,17,21,25-29,31-34,36-44,51-53H,16,18-20,22-24H2,1-12H3/b14-13+,17-15+/t25-,26-,27-,28-,29+,31+,32+,33+,34-,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1
• SMILES isoméricas: C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)OC(=O)C)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O[C@H]4CC[C@@H]([C@H](O4)C)N(C)C
• PubChem CID: 49787020
• Peso molecular: 885.1

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Aminosaccharides
          • Level6 Aminoglycosides

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Aminosaccharides
• Direct Parent: Aminoglycosides
• Alternative Parents: Macrolides and analogues Disaccharides O-glycosyl compounds Dicarboxylic acids and derivatives Oxanes Alpha-hydrogen aldehydes Tertiary alcohols 1,2-aminoalcohols Trialkylamines Amino acids and derivatives Carboxylic acid esters Secondary alcohols Lactones Acetals Oxacyclic compounds Dialkyl ethers Hydrocarbon derivatives Organopnictogen compounds Organic oxides
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Aminoglycoside core - Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Dicarboxylic acid or derivatives - Oxane - Alpha-hydrogen aldehyde - Tertiary alcohol - Carboxylic acid ester - 1,2-aminoalcohol - Lactone - Amino acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Secondary alcohol - Dialkyl ether - Organoheterocyclic compound - Carboxylic acid derivative - Oxacycle - Ether - Acetal - Organic oxide - Carbonyl group - Organic nitrogen compound - Organopnictogen compound - Amine - Alcohol - Aldehyde - Organonitrogen compound - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
• External Descriptors: Ansamycins and related polyketides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (não humanos)

Toxoplasma gondii (4585 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Soluble in water (1:50), ethanol (8.2 mg/ml), chloroform, methanol, and DMSO.
• Índice de refração: n20D1.54
• Rotação específica [α]: α20/D -87.8°, c = 1 in methanol; α20/D -86°, c = 0.82 in ethanol
• Ponto de ebulição (°C): 916.68° C
• Ponto de fusão (°C): 120-122° C
• Peso molecular: 885.100 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 17
• Rotatable Bond Count: 13
• Exact Mass: 884.525 Da
• Monoisotopic Mass: 884.525 Da
• Topological Polar Surface Area: 201.000 Ų
• Heavy Atom Count: 62
• Formal Charge: 0
• Complexity: 1480.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 19
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 1

Referências

1. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen.  (2021)  Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner.  Foods,  10  (8): (1838).  [PMID:34441616] [10.3390/foods10081838]

2. Gu Yiwen, Lin Xiu, Lu Yanxu, Fang Shuguang, Hu Kun, Ju Xin, Li Liangzhi, Chen Zhi.  (2025)  Screening of Antibiotic-Sensitive Lactic Acid Bacteria (LAB) Associated with the Gut of Penaeus Vannamei and its Application in Shrimp Farming.  CURRENT MICROBIOLOGY,  82  (9): (1-11).  [PMID:40681798] [10.1007/s00284-025-04396-7]