Acridine - ≥98% , DNA disrupting agent, CAS No.260-94-6, DNA disrupting agent

CAS: 260-94-6 Cat. No.: A106024 Fórmula: C₁₃H₉N Peso molecular: 179.22 Beilstein Registry Number: 120200 Número CE: 205-971-6

GRAU & PUREZA ≥98%

Synonyms

10-Azaanthracene|UPCMLD-DP077:001|ACRIDINE|Benzo[b]quinoline|acridine acid|Akridin [Czech]|2,3-Benzoquinoline|ACRIDINE [MI]|Benzoquinolinylidene|2,3,5,6-Dibenzopyridine|9-Azaanthracene|Benzo(b)quinoline|Dibenzo(b,e)pyridine|Coal tar pitch volatiles: acridine|Acridines|Acridine (purified by sublimation)|Akridin|Acrydine|ACRIDINE (1,2,3,4,5,6,7,8,9-D9)|Acridine [UN2713] [Poison]

Storage

Room temperature

Shipped In

FedEx DG Service

Visão geral

The fluorescence intensity, fluorescence quantum yield, time of decay, and lifetime are dependent upon the solvent. For example, the fluorescence intensity varies from being moderately strong in aqueous solution and very weak in hydrocarbon solvents. Addit

Especificações

Sinónimos

10-Azaanthracene | UPCMLD-DP077:001 | ACRIDINE | Benzo[b]quinoline | acridine acid | Akridin [Czech] | 2,3-Benzoquinoline | ACRIDINE [MI] | Benzoquinolinylidene | 2,3,5,6-Dibenzopyridine | 9-Azaanthracene | Benzo(b)quinoline | Dibenzo(b,e)pyridine | Coal tar pitch volatiles: acridine | Acridines | Acridine (purified by sublimation) | Akri Show more

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Nucleic acid phosphate is a small cationic planar dye that mainly binds to RNA and DNA. Used for nucleic acid staining, especially cell cycle determination

Condições de armazenamento de armazenamento

Room temperature

Enviado em

FedEx DG Service

Tipo de ação

DISRUPTING AGENT

Mecanismo de ação

DNA disrupting agent

Pureza

≥98%

Propriedades do produto

ALogP

3.4

Nomes e identificadores

Pubchem Sid

488180942

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180942

Sorrisos canónicos

C1=CC=C2C(=C1)C=C3C=CC=CC3=N2

IUPAC Name

acridine

InChIKey

DZBUGLKDJFMEHC-UHFFFAOYSA-N

INCHI

1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H

SMILES isoméricas

C1=CC=C2C(=C1)C=C3C=CC=CC3=N2

WGK Alemanha

3

RTECS

AR7175000

Número UN

2713

Grupo de embalagem

III

Peso molecular

179.22

Beilstein

120200

Reaxy-Rn

120200

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=120200&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Quinolines and derivatives
      • Subclass Benzoquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Quinolines and derivatives
• Subclass: Benzoquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Acridines
• Alternative Parents: Pyridines and derivatives Benzenoids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Acridine - Benzenoid - Pyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring.
• External Descriptors: acridines - polycyclic heteroarene - mancude organic heterotricyclic parent

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)

Discover Target: TOP2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)

Discover Target: HTR3A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLA Tclin Alpha-galactosidase A (5444 Activities)

Discover Target: GLA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A2780 (11979 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FEN1 Tchem Flap endonuclease 1 (12055 Activities)

Discover Target: FEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

Discover Target: SMAD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Alvos associados (não humanos)

L1210 (27553 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Calf thymus DNA (4845 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Very soluble in Ethanol,Ether,Benzene,Alcohol
• Ponto de ebulição (°C): 345-346°C
• Ponto de fusão (°C): 111°C
• Peso molecular: 179.220 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 179.073 Da
• Monoisotopic Mass: 179.073 Da
• Topological Polar Surface Area: 12.900 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 181.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1