Brand: Aladdin Scientific
SKU: A607602
Availability: InStock

AMG28 - Moligand™ , Inhibitor of mitogen-activated protein kinase kinase kinase 14;Inhibitor of p21 (RAC1) activated kinase 4;Inhibitor of p21 (RAC1) activated kinase 5;Inhibitor of p21 (RAC1) activated kinase 6;Inhibitor of phosphoinositide kinase; FYVE-, Inhibitor of mitogen-activated protein kinase kinase kinase 14;Inhibitor of p21 (RAC1) activated kinase 4;Inhibitor of p21 (RAC1) activated kinase 5;Inhibitor of p21 (RAC1) activated kinase 6;Inhibitor of phosphoinositide kinase; FYVE-type zinc finger con

CAS: A607602 Cat. No.: A607602 PubChem CID: 58221549

Especificações Nomes e identificadores Dados avançados Taxonomic Classification Estrutura 3D Alvos associados (humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Calculadoras de soluções Revisões

Especificações

Especificações e pureza

Moligand™

Condições de armazenamento de armazenamento

Room temperature

Grau

Moligand™

Tipo de ação

INHIBITOR

Mecanismo de ação

Inhibitor of mitogen-activated protein kinase kinase kinase 14;Inhibitor of p21 (RAC1) activated kinase 4;Inhibitor of p21 (RAC1) activated kinase 5;Inhibitor of p21 (RAC1) activated kinase 6;Inhibitor of phosphoinositide kinase; FYVE-type zinc finger con

Nomes e identificadores

Sorrisos canónicos

CC(C)(C#Cc1cc2c(cc1)[nH]c1c2c2c(CCC1)cnc(n2)N)O

InChIKey

DGLFSNZWRYADFC-UHFFFAOYSA-N

INCHI

1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)

SMILES isoméricas

CC(C)(C#CC1=CC2=C(C=C1)NC3=C2C4=NC(=NC=C4CCC3)N)O

PubChem CID

58221549

Dados avançados

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Classe Indoles and derivatives
    - Subclass Indoles

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Classe	Indoles and derivatives
Subclass	Indoles
Intermediate Tree Nodes	Not available
Direct Parent	Indoles
Alternative Parents	Aminopyrimidines and derivatives Ynones Benzenoids Tertiary alcohols Pyrroles Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Indole - Aminopyrimidine - Pyrimidine - Ynone - Benzenoid - Pyrrole - Tertiary alcohol - Heteroaromatic compound - Azacycle - Alcohol - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as indoles. These are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Alvos associados (humanos)

PAK5 Tchem Serine/threonine-protein kinase PAK 5 (0 Activities)

Discover Target: PAK5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIKFYVE Tchem 1-phosphatidylinositol 3-phosphate 5-kinase (0 Activities)

Discover Target: PIKFYVE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TTBK1 Tbio Tau-tubulin kinase 1 (0 Activities)

Discover Target: TTBK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAOK1 Tchem Serine/threonine-protein kinase TAO1 (0 Activities)

Discover Target: TAOK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAOK2 Tchem Serine/threonine-protein kinase TAO2 (0 Activities)

Discover Target: TAOK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAOK3 Tchem Serine/threonine-protein kinase TAO3 (0 Activities)

Discover Target: TAOK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAP3K14 Tchem Mitogen-activated protein kinase kinase kinase 14 (0 Activities)

Discover Target: MAP3K14

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PAK4 Tchem Serine/threonine-protein kinase PAK 4 (0 Activities)

Discover Target: PAK4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PAK6 Tchem Serine/threonine-protein kinase PAK 6 (0 Activities)

Discover Target: PAK6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK2 Tclin Tyrosine-protein kinase JAK2 (12915 Activities)

Discover Target: JAK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP2K4 Tchem Dual specificity mitogen-activated protein kinase kinase 4 (1051 Activities)

Discover Target: MAP2K4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PAK6 Tchem Serine/threonine-protein kinase PAK6 (1915 Activities)

Discover Target: PAK6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PAK5 Tchem Serine/threonine-protein kinase PAK7 (1760 Activities)

Discover Target: PAK5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP4K5 Tchem Mitogen-activated protein kinase kinase kinase kinase 5 (1523 Activities)

Discover Target: MAP4K5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PAK4 Tchem Serine/threonine-protein kinase PAK 4 (3212 Activities)

Discover Target: PAK4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP4K2 Tchem Mitogen-activated protein kinase kinase kinase kinase 2 (2692 Activities)

Discover Target: MAP4K2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAOK1 Tchem Serine/threonine-protein kinase TAO1 (2019 Activities)

Discover Target: TAOK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MYLK4 Tchem Myosin light chain kinase family member 4 (320 Activities)

Discover Target: MYLK4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CIT Tchem Citron Rho-interacting kinase (570 Activities)

Discover Target: CIT

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRKX Tchem Serine/threonine-protein kinase PRKX (2278 Activities)

Discover Target: PRKX

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP3K14 Tchem Mitogen-activated protein kinase kinase kinase 14 (1412 Activities)

Discover Target: MAP3K14

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP3K3 Tchem Mitogen-activated protein kinase kinase kinase 3 (562 Activities)

Discover Target: MAP3K3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSSK1B Tchem Testis-specific serine/threonine-protein kinase 1 (2038 Activities)

Discover Target: TSSK1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAOK3 Tchem Serine/threonine-protein kinase TAO3 (1005 Activities)

Discover Target: TAOK3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP3K2 Tchem Mitogen-activated protein kinase kinase kinase 2 (593 Activities)

Discover Target: MAP3K2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAP3K19 Tchem SPS1/STE20-related protein kinase YSK4 (285 Activities)

Discover Target: MAP3K19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAOK2 Tchem Serine/threonine-protein kinase TAO2 (964 Activities)

Discover Target: TAOK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIP4K2C Tchem Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma (641 Activities)

Discover Target: PIP4K2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIP5K1C Tchem Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (331 Activities)

Discover Target: PIP5K1C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DSTYK Tchem Dual serine/threonine and tyrosine protein kinase (235 Activities)

Discover Target: DSTYK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TTBK1 Tbio Tau-tubulin kinase 1 (179 Activities)

Discover Target: TTBK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIKFYVE Tchem 1-phosphatidylinositol 3-phosphate 5-kinase (270 Activities)

Discover Target: PIKFYVE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Certificados（CoA,COO,BSE/TSE e Mapa de Análise)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Calculadoras de soluções

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Revisões

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