Amino-PEG4-CH2COOH - ≥95% , CAS No.195071-49-9

CAS: 195071-49-9 Cat. No.: A412460 Fórmula: C₁₀H₂₁NO₆ Peso molecular: 251.28

GRADE & PURITY ≥95%

Synonyms

3,6,9,12-Tetraoxatetradecanoic acid, 14-amino- | 14-amino-3,6,9,12-tetraoxatetradecanoic acid | H2N-PEG4-CH2COOH | NH2-PEG4-CH2COOH | SCHEMBL1170690 | Amine-PEG4-CH2COOH | AKOS028109928 | Amino-PEG4-CH2COOH | BS-25456 | s10597 | 14-Amino-3,6,9,12-tetraoxa

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Visão geral

Information

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Specifications

Sinónimos

3,6,9,12-Tetraoxatetradecanoic acid, 14-amino- | 14-amino-3,6,9,12-tetraoxatetradecanoic acid | H2N-PEG4-CH2COOH | NH2-PEG4-CH2COOH | SCHEMBL1170690 | Amine-PEG4-CH2COOH | AKOS028109928 | Amino-PEG4-CH2COOH | BS-25456 | s10597 | 14-Amino-3,6,9,12-tetraoxa

Especificações e pureza

≥95%

Mecanismos bioquímicos e fisiológicos

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥95%

Nomes e identificadores

Pubchem Sid

528763298

Sorrisos canónicos

C(COCCOCCOCCOCC(=O)O)N

IUPAC Name

2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid

InChIKey

NPRAKTLKDKKZAV-UHFFFAOYSA-N

INCHI

1S/C10H21NO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9,11H2,(H,12,13)

SMILES isoméricas

C(COCCOCCOCCOCC(=O)O)N

Peso molecular

251.28

Reaxy-Rn

20360792

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20360792&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Amino acids
• Alternative Parents: Monocarboxylic acids and derivatives Dialkyl ethers Carboxylic acids Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Amino acid - Carboxylic acid - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organic oxygen compound - Aliphatic acyclic compound
• Descrição: This compound belongs to the class of organic compounds known as amino acids. These are organic compounds that contain at least one carboxyl group and one amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro
• Sensibilidade: 对光敏感
• Peso molecular: 251.280 g/mol
• XLogP3: -4.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 13
• Exact Mass: 251.137 Da
• Monoisotopic Mass: 251.137 Da
• Topological Polar Surface Area: 100.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 178.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1