γ-Aminobutyric acid（GABA） - BioReagent, ≥99% , CAS No.56-12-2

CAS: 56-12-2 Cat. No.: A755686 Fórmula: C₄H₉NO₂ Peso molecular: 103.12 Beilstein Registry Number: 4(3)1316 Número CE: 200-258-6

GRADE & PURITY BioReagent, ≥99%

Synonyms

NSC45460 | DF 468 | 3-Carboxypropylamine | Gammalone | gamma Aminobutyric acid | GABA | 4-amino-n-butyric acid | butanoic acid, 4-amino- | gamma-Aminobutryic acid | EPA Pesticide Chemical Code 030802 | UNII-2ACZ6IPC6I | Aminobutyric acid,-4-

Storage

Room temperature

Shipped In

Normal

Visão geral

γ-Aminobutyric acid (GABA) is a non-protein amino acid associated with the brain. Being synthesized in the nervous system, it is packed into synaptic vesicles. It is present naturally in green tea, soybean, germinated rice, and in some fermented foods.

Application:

γ-Aminobutyric acid (GABA) has been used to treat dorsal root ganglion neurons for electrophysiological recordings studies to test its effect on neuropathic pain in rats. It has also been used to test its protective effects in an ex vivo machine perfusion system of small-for-size grafts (SFSG) injury model.

Specifications

Sinónimos

NSC45460 | DF 468 | 3-Carboxypropylamine | Gammalone | gamma Aminobutyric acid | GABA | 4-amino-n-butyric acid | butanoic acid, 4-amino- | gamma-Aminobutryic acid | EPA Pesticide Chemical Code 030802 | UNII-2ACZ6IPC6I | Aminobutyric acid,-4-

Especificações e pureza

BioReagent, ≥99%

Mecanismos bioquímicos e fisiológicos

γ-Aminobutyric acid (GABA) is a mammalian inhibitory neurotransmitter with multiple functions. It is crucial for the normal central nervous system (CNS) functioning. A few documented functions of GABA include its protective role in toxin-induced damage. I

Condições de armazenamento de armazenamento

Room temperature

Enviado em

Normal

Grau

BioReagent

Pureza

≥99%

Nomes e identificadores

Pubchem Sid

528768894

Sorrisos canónicos

C(CC(=O)O)CN

IUPAC Name

4-aminobutanoic acid

InChIKey

BTCSSZJGUNDROE-UHFFFAOYSA-N

INCHI

1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

SMILES isoméricas

C(CC(=O)O)CN

WGK Alemanha

2

RTECS

ES6300000

CAS alternativo

56-12-2,70582-09-1 (calcium salt (2:1))

Número NSC

27418

Termos de entrada MeSH

4 Aminobutanoic Acid;4 Aminobutyric Acid;4-Aminobutanoic Acid;4-Aminobutyric Acid;Acid, Hydrochloride gamma-Aminobutyric;Aminalon;Aminalone;GABA;GABA, Lithium;gamma Aminobutyric Acid;gamma Aminobutyric Acid, Hydrochloride;gamma Aminobutyric Acid, Monolith

Peso molecular

103.12

Beilstein

4(3)1316

Reaxy-Rn

906818

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=906818&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Gamma amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Gamma amino acids and derivatives
• Alternative Parents: Amino fatty acids Straight chain fatty acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Gamma amino acid or derivatives - Amino fatty acid - Straight chain fatty acid - Fatty acid - Fatty acyl - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Amine - Hydrocarbon derivative - Aliphatic acyclic compound
• Descrição: This compound belongs to the class of organic compounds known as gamma amino acids and derivatives. These are amino acids having a (-NH2) group attached to the gamma carbon atom.
• External Descriptors: Amino fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: H 2 O: 0.5 M at 20 °C, clear, colorless
• Ponto de fusão (°C): 195°C
• Peso molecular: 103.120 g/mol
• XLogP3: -3.200
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 103.063 Da
• Monoisotopic Mass: 103.063 Da
• Topological Polar Surface Area: 63.300 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 62.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1