Berotralstat dihydrochloride - ≥98% , Plasma kallikrein inhibitor, CAS No.1809010-52-3, Plasma kallikrein inhibitor

CAS: 1809010-52-3 Cat. No.: B650745 Fórmula: C₃₀H₂₈Cl₂F₄N₆O Peso molecular: 635.48 Número CE: 189-048-2 PubChem CID: 139030242

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Argon charged,Desiccated

Shipped In

Wet ice

Visão geral

Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.

Form:Solid

Specifications

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by bloc

Condições de armazenamento de armazenamento

Store at 2-8°C,Argon charged,Desiccated

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Mecanismo de ação

Plasma kallikrein inhibitor

Pureza

≥98%

Nomes e identificadores

Sorrisos canónicos

C1CC1CN[C@@H](C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N.Cl.Cl

SMILES isoméricas

C1CC1CN[C@@H](C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N.Cl.Cl

PubChem CID

139030242

Peso molecular

635.48

Propriedades químicas e físicas

• Solubilidade: DMSO : 120 mg/mL (188.83 mM; Need ultrasonic)