≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Biotin-PEG3-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
| Sorrisos canónicos | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2 |
|---|---|
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]pentanamide |
| InChIKey | ZWFOOMQCYIGZBE-ZOBUZTSGSA-N |
| INCHI | 1S/C18H32N6O5S/c19-24-21-6-8-28-10-12-29-11-9-27-7-5-20-16(25)4-2-1-3-15-17-14(13-30-15)22-18(26)23-17/h14-15,17H,1-13H2,(H,20,25)(H2,22,23,26)/t14-,15-,17-/m0/s1 |
| SMILES isoméricas | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2 |
| Peso molecular | 444.55 |
| Reaxy-Rn | 19578611 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19578611&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Sensibilidade | Light sensitive |
|---|---|
| Ponto de fusão (°C) | 110 °C |
| Peso molecular | 444.600 g/mol |
| XLogP3 | 0.500 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 17 |
| Exact Mass | 444.215 Da |
| Monoisotopic Mass | 444.215 Da |
| Topological Polar Surface Area | 138.000 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 577.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiang Yongpeng, Huang Jie, Tian Kai, Yi Xiao, Zheng Haonan, Zhu Yi, Guo Tiannan, Ji Xiong. (2022) Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture. GENOME BIOLOGY, 23 (1): (1-37). [PMID:36443871] [10.1186/s13059-022-02812-w] |
| 2. Zhan Yujuan, Chen Qiugu, Song Yue, Wei Xianli, Zhao Tingxiu, Chen Bonan, Li Chengxi, Zhang Wenbo, Jiang Yanjun, Tan Yuhui, Du Biaoyan, Xiao Jianyong, Wang Kun. (2022) Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells. CELL BIOLOGY AND TOXICOLOGY, [PMID:36070022] [10.1007/s10565-022-09756-8] |
| 3. Zhai Yansheng, Huang Xiaoyan, Zhang Keren, Huang Yuchen, Jiang Yanlong, Cui Jingwei, Zhang Zhe, Chiu Cookson K. C., Zhong Weiye, Li Gang. (2022) Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling. Nature Communications, 13 (1): (1-12). [PMID:35987950] [10.1038/s41467-022-32689-z] |
| 4. Chenchen Ge, Xiong Chen, Dou Wang. (2024) An array of femtoliter wells for sensitive detection of copper using click chemistry. TALANTA, [PMID:38537359] [10.1016/j.talanta.2024.125973] |
| 5. Yu-Juan Zhan, Chun-Miao Deng, Lin Tang, Shu-Jun Li, Tao-Yang Xu, Xian Wei, Xin-Yi Zhang, Can-Can Zheng, Li Deng, Cui Shao, Zhong-Min Ouyang, Alfred King-Yin Lam, Rong Zhang, Jun Liu, Xing-Yuan Shi, Zhen-Yu Pan, Wei Dai, Ming-Liang He, Simon Law, Xu Li, Xiao-Bing Chen, Cheng Zhou, Bin Li, Wen-Wen Xu. (2025) NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA. Advanced Science, [PMID:40729677] [10.1002/advs.202502931] |
| 6. Shaoqian Ma, Yantao Hong, Junhan Chen, Jingzhao Xu, Xiaohua Shen. (2025) Single-cell nascent transcription reveals sparse genome usage and plasticity. CELL, [PMID:41015043] [10.1016/j.cell.2025.09.003] |
| 7. Meichen Li, Yi Peng, Qingqing Xiao, Siyi Chen, Chunjie Zhang, Hongyu Chen, Yue Zhao, Shan Chang, Lu Qiu, Lele Zhang, Xiaoqiang Guo, Qiang Fu. (2025) Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis. PHYTOMEDICINE, [PMID:41447841] [10.1016/j.phymed.2025.157729] |
| 8. Yuchen Huang, Lexuan Hou, Lin Zhu, Xi Yang, Gang Li. (2026) Protocol for covalent ligand discovery via library-versus-proteome screening. STAR Protocols, 7 (3): (104786). [PMID:] [10.1016/j.xpro.2026.104786] |
