BOP, Antagonist of integrin α4β1;Antagonist of integrin; alpha 9 subunit, CAS No.217453-20-8, Antagonist of integrin α4β1;Antagonist of integrin; alpha 9 subunit

CAS: 217453-20-8 Cat. No.: rp173588 PubChem CID: 10301396
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Size
Alemanha (EU)
USA*
Price
Qty
500μg
rp173588-500μg
Sob encomenda · 8–12 semanas
2082,49€
1mg
rp173588-1mg
Sob encomenda · 8–12 semanas
3470,87€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
BOP, Antagonist of integrin α4β1;Antagonist of integrin; alpha 9 subunit, CAS No.217453-20-8
Sinónimos
compound 2;compound 3;N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine
Grau
Moligand™
Especificações e pureza
Moligand™
Tipo de ação
ANTAGONIST
Mecanismo de ação
Antagonist of integrin α4β1;Antagonist of integrin; alpha 9 subunit
CAS
217453-20-8
Tipo de molécula
Small molecule
Armazenamento e envio
Condições de armazenamento de armazenamento
Room temperature

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct ParentDipeptides
Alternative Parents Phenylalanine and derivatives  Proline and derivatives  N-acyl-L-alpha-amino acids  Alpha amino acid amides  Phenylpropanoic acids  Amphetamines and derivatives  Benzenesulfonamides  Benzenesulfonyl compounds  Pyrrolidinecarboxamides  Pyrrolidine carboxylic acids  Phenoxy compounds  Organosulfonamides  Sulfonyls  Carbamate esters  Secondary carboxylic acid amides  Carboxylic acids  Azacyclic compounds  Monocarboxylic acids and derivatives  Carbonyl compounds  Organic oxides  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Alpha-dipeptide - Phenylalanine or derivatives - Proline or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - N-acyl-alpha-amino acid - Alpha-amino acid amide - 3-phenylpropanoic-acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Benzenesulfonamide - Benzenesulfonyl group - Phenoxy compound - Pyrrolidine carboxylic acid - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Monocyclic benzene moiety - Benzenoid - Organosulfonic acid amide - Pyrrolidine - Sulfonyl - Carbamic acid ester - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Organoheterocyclic compound - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
ITGA4 Tclin Integrin alpha-4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA9 Tbio Integrin alpha-9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB1 Tclin Integrin beta-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB1 Tclin Integrin alpha-4/beta-1 (2269 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Informação genética
Alternate Namescompound 2;compound 3;N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more
Citations of This Product
Referências
1. Kai Feng, Yiling Ruan, Xinmiao Zhang, Xiaojing Wu, Zixuan Liu, Xiaolian Sun.  (2023)  Photothermal-Ionic-Pharmacotherapy of Myocardial Infarction with Enhanced Angiogenesis and Antiapoptosis.  ACS Applied Materials & Interfaces,      [PMID:38031235] [10.1021/acsami.3c14109]
2. Jia Zeng, Peng Sun, Xinning Fang, Yicheng Jiang, Zhenghong Wu, Xiaole Qi.  (2023)  “Shell-Core” Bilayer Nanoparticle as Chemotherapeutic Drug Co-Delivery Platforms Render Synchronized Microenvironment Respond and Enhanced Antitumor Effects.  International Journal of Nanomedicine,      [PMID:36998602] [10.2147/IJN.S401038]
3. Kai-Xian Hu, Ze-Yong Zhao, Peng Lu, Shuang He, Cong Deng, Yu-Zhong Wang.  (2023)  Caffeic acid decorated ammonium polyphosphate-based flame retardant for fire safety and anti-aging of wood plastic composites.  POLYMER DEGRADATION AND STABILITY,      [PMID:] [10.1016/j.polymdegradstab.2023.110275]
4. Jiangbo Guo, Yajuan Li, Yajun Zhang, Jujie Ren, Xudong Yu, Xinhua Cao.  (2021)  Switchable Supramolecular Configurations of Al3+/LysTPY Coordination Polymers in a Hydrogel Network Controlled by Ultrasound and Heat.  ACS Applied Materials & Interfaces,      [PMID:34379399] [10.1021/acsami.1c10150]
Calculadoras de soluções
Revisões

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