C 021 dihydrochloride - ≥99%(HPLC) , CAS No.1784252-84-1

CAS: 1784252-84-1 Cat. No.: C288233 Fórmula: C27H41N5O2•2HCl Peso molecular: 540.57 PubChem CID: 56972238
Disponível para encomenda
GRADE & PURITY ≥99%(HPLC)
Synonyms
2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
★
Size
Alemanha (EU)
USA*
Price
Qty
5mg
C288233-5mg
—
5 Em stock

115,32€

173,46€
Gravar 58,14 € (33.52%)
10mg
C288233-10mg
—
5 Em stock

184,74€

277,59€
Gravar 92,85 € (33.45%)
25mg
C288233-25mg
—
3 Em stock

405,15€

608,20€
Gravar 203,05 € (33.39%)
50mg
C288233-50mg
—
2 Em stock

769,60€

1154,87€
Gravar 385,28 € (33.36%)
100mg
C288233-100mg
—
2 Em stock

1385,69€

2079,02€
Gravar 693,32 € (33.35%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Product description:

C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.

Specifications

Sinónimos
2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Especificações e pureza
≥99%(HPLC)
Mecanismos bioquímicos e fisiológicos
Potent CCR4 chemokine receptor antagonist (IC50values are 0.14 and 0.039μM for inhibition of chemotaxis in human and mouse respectively).
Condições de armazenamento de armazenamento
Store at -20°C,Desiccated
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
ANTAGONIST
Pureza
≥99%(HPLC)
Nomes e identificadores
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488201805
Sorrisos canónicos
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl
IUPAC Name
N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine;dihydrochloride
InChIKey
GKJKNYQUFAPLOQ-UHFFFAOYSA-N
INCHI
1S/C27H41N5O2.2ClH/c1-33-24-18-22-23(19-25(24)34-2)29-27(30-26(22)28-20-10-6-3-4-7-11-20)32-16-12-21(13-17-32)31-14-8-5-9-15-31;;/h18-21H,3-17H2,1-2H3,(H,28,29,30);2*1H
SMILES isoméricas
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl
PubChem CID
56972238
Peso molecular
540.57

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseDiazanaphthalenes
SubclassBenzodiazines
Intermediate Tree Nodes Quinazolines
Direct ParentQuinazolinamines
Alternative Parents Dialkylarylamines  Anisoles  Aminopyrimidines and derivatives  Aminopiperidines  Alkyl aryl ethers  Imidolactams  Heteroaromatic compounds  Trialkylamines  Azacyclic compounds  Hydrochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinazolinamine - Anisole - Phenol ether - Dialkylarylamine - Alkyl aryl ether - 4-aminopiperidine - Aminopyrimidine - Imidolactam - Benzenoid - Pyrimidine - Piperidine - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Azacycle - Ether - Organonitrogen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Hydrochloride - Aromatic heteropolycyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDataItem
E23181048Certificate of AnalysisMar 10, 2026 C288233
E23181052Certificate of AnalysisMar 10, 2026 C288233
E23181057Certificate of AnalysisMar 10, 2026 C288233
E23181060Certificate of AnalysisMar 10, 2026 C288233
E23181063Certificate of AnalysisMar 10, 2026 C288233
E23181065Certificate of AnalysisMar 10, 2026 C288233
E23181066Certificate of AnalysisMar 10, 2026 C288233
E23181069Certificate of AnalysisMar 10, 2026 C288233
E23181071Certificate of AnalysisMar 10, 2026 C288233
E23181074Certificate of AnalysisMar 10, 2026 C288233
Propriedades químicas e físicas
SolubilidadeSolvent:water, Max Conc. mg/mL: 26.96, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 53.93, Max Conc. mM: 100
SensibilidadeMoisture sensitive
Peso molecular540.600 g/mol
XLogP3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass539.279 Da
Monoisotopic Mass539.279 Da
Topological Polar Surface Area62.800 Ų
Heavy Atom Count36
Formal Charge0
Complexity602.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count3
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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