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Naringin - Moligand™, ≥95% , CAS No.10236-47-2

CAS: 10236-47-2 Cat. No.: N107345 Fórmula: C27H32O14 Peso molecular: 580.53 Beilstein Registry Number: 102012 Número CE: 233-566-4
83 Citations COA
Naringin - Moligand™, ≥95% CAS No(10236-47-2) by Aladdin Scientific
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
Synonyms
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside | (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-betaD-glucopyranos
Storage
Room temperature,Argon charged
Shipped In
Normal
★
Size
Alemanha (EU)
USA*
Price
Qty
5g
N107345-5g
—
5 Em stock
8,59€
25g
N107345-25g
—
6 Em stock
25,95€
100g
N107345-100g
—
3 Em stock

40,70€

72,80€
Gravar 32,11 € (44.10%)
500g
N107345-500g
—
1 Em stock

140,49€

255,03€
Gravar 114,54 € (44.91%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ Lista de desejos ⇅ Adicionar à Comparação ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Visão geral Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas FAQs e artigos Citations of This Product Calculadoras de soluções Revisões
🧪
Why this grade

Moligand™, ≥95% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Argon charged Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 83 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Naringin has been used:
• as a bitter tastant to compare the behavioral response of the Drosophila larva and adult
• to study its anti-inflammatory property and to determine its effect on nucleus pulposus (NP) cells
• to determine its effect on bone metabolism like osteogenic differentiation, inhibition of osteoclast formation

Specifications

Sinónimos
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside | (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-betaD-glucopyranos
Especificações e pureza
Moligand™, ≥95%
Mecanismos bioquímicos e fisiológicos
Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time.
Condições de armazenamento de armazenamento
Room temperature,Argon charged
Enviado em
Normal
Grau
Moligand™
Pureza
≥95%
Nomes e identificadores
Pubchem Sid488189790
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189790
Sorrisos canónicosCC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
IUPAC Name(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
InChIKeyDFPMSGMNTNDNHN-ZPHOTFPESA-N
INCHI1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
SMILES isoméricas C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
WGK Alemanha 3
RTECS QN6340000
Peso molecular 580.53
Beilstein 102012
Reaxy-Rn 25075985
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25075985&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClasseFlavonoids
SubclassFlavonoid glycosides
Intermediate Tree Nodes Flavonoid O-glycosides
Direct ParentFlavonoid-7-O-glycosides
Alternative Parents 4'-hydroxyflavonoids  5-hydroxyflavonoids  Flavanones  Phenolic glycosides  Chromones  Disaccharides  O-glycosyl compounds  Aryl alkyl ketones  1-hydroxy-2-unsubstituted benzenoids  1-hydroxy-4-unsubstituted benzenoids  Alkyl aryl ethers  Oxanes  Benzene and substituted derivatives  Vinylogous acids  Secondary alcohols  Polyols  Acetals  Oxacyclic compounds  Primary alcohols  Hydrocarbon derivatives  Organic oxides  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Flavonoid-7-o-glycoside - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - Flavanone - Hydroxyflavonoid - Flavan - Phenolic glycoside - Chromone - Disaccharide - Glycosyl compound - O-glycosyl compound - Chromane - Benzopyran - 1-benzopyran - Aryl alkyl ketone - Aryl ketone - Phenol - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - 1-hydroxy-4-unsubstituted benzenoid - Oxane - Benzenoid - Monocyclic benzene moiety - Vinylogous acid - Secondary alcohol - Ketone - Polyol - Acetal - Organoheterocyclic compound - Oxacycle - Ether - Primary alcohol - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Alcohol - Organooxygen compound - Aromatic heteropolycyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position.
External Descriptors flavanones
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
SLCO1A2 Tchem Solute carrier organic anion transporter family member 1A2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FABP4 Tchem Fatty acid binding protein adipocyte (764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPSE Tchem Heparanase (634 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Monocyte (474 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UBE2N Tchem Ubiquitin-conjugating enzyme E2 N (1570 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCL2A1 Tchem Bcl-2-related protein A1 (291 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1A2 Tchem Solute carrier organic anion transporter family member 1A2 (104 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYCS Tchem Cytochrome c (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNJ3 Tchem Kir3.1/Kir3.4 (583 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNJ3 Tchem Kir3.1/Kir3.2 (445 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aggregatibacter actinomycetemcomitans (150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Porphyromonas gingivalis (651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a5 Solute carrier organic anion transporter family member 1A5 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Thoracic aorta (838 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados（CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeDataItem
A2306768Certificate of AnalysisSep 22, 2026 N107345
A2306769Certificate of AnalysisSep 22, 2026 N107345
A2306786Certificate of AnalysisSep 22, 2026 N107345
C2209103Certificate of AnalysisDec 10, 2025 N107345
L2522675Certificate of AnalysisNov 29, 2025 N107345
L2511705Certificate of AnalysisNov 29, 2025 N107345
L2511704Certificate of AnalysisNov 29, 2025 N107345
L2511637Certificate of AnalysisNov 29, 2025 N107345
F2629030Certificate of AnalysisNov 29, 2025 N107345
F2516452Certificate of AnalysisMay 06, 2025 N107345
F2516453Certificate of AnalysisMay 06, 2025 N107345
F2516468Certificate of AnalysisMay 06, 2025 N107345
D2426035Certificate of AnalysisDec 05, 2022 N107345
E2420024Certificate of AnalysisDec 05, 2022 N107345
E2508473Certificate of AnalysisDec 05, 2022 N107345
H2328079Certificate of AnalysisDec 05, 2022 N107345
L2403254Certificate of AnalysisDec 05, 2022 N107345
A2306792Certificate of AnalysisDec 05, 2022 N107345
A2306788Certificate of AnalysisDec 05, 2022 N107345
A2306787Certificate of AnalysisDec 05, 2022 N107345
A2306767Certificate of AnalysisDec 05, 2022 N107345
C2209102Certificate of AnalysisFeb 14, 2022 N107345
D2417028Certificate of AnalysisFeb 14, 2022 N107345
A2508089Certificate of AnalysisFeb 14, 2022 N107345
L2301115Certificate of AnalysisFeb 14, 2022 N107345
Propriedades químicas e físicas
SolubilidadeSoluble in water, alcohol, acetone and warm acetic acid
SensibilidadeMoisture sensitive
Rotação específica [α]-84 ° (C=2, EtOH)
Ponto de fusão (°C)166℃
Peso molecular580.500 g/mol
XLogP3-0.500
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Exact Mass580.179 Da
Monoisotopic Mass580.179 Da
Topological Polar Surface Area225.000 Ų
Heavy Atom Count41
Formal Charge0
Complexity884.000
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs e artigos
Molecular Basis of Glycosylation Modification and Functional Release in Natural Products
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Natural products glycosylation modification glycosyltransferases glycosidases precursor activation functional release deglycosylation structure-activity relationship
Extraction Methods and Process Selection for Flavonoid Compounds
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
flavonoid compounds extraction methods solvent extraction ultrasound-assisted extraction microwave-assisted extraction enzyme-assisted extraction supercritical fluid extraction process optimization
Mechanisms by Which Flavonoid Natural Products Regulate the Oxidative Stress-Inflammation Axis
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Inflammation Natural products Oxidative Stress Reactive oxygen species Nrf2 NLRP3 flavonoids NF-kappaB
Citations of This Product
How to Cite Aladdin Scientific Products? Citations Search
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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