CER6-2’R-d - ≥99% , CAS No.2260670-10-6

CAS: 2260670-10-6 Cat. No.: C1446834 Fórmula: C₃₄H₆₀D₉NO₅ Peso molecular: 580.97

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

CER6-2’R-d 9 is deuterium labeled CER6-2’R.

Specifications

Especificações e pureza

≥99%

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥99%

Nomes e identificadores

Peso molecular

580.97

Application Protocols

No tested applications or protocols are provided for CER6-2’R-d in the Product Data.

General starting points (to be adapted once identity and solubility are known)

• Stock solutions: Prepare 10–100 mM in DMSO or another compatible solvent; filter (0.22 μm PTFE) and store aliquots at -20 °C.
• Working solutions: Dilute into assay medium immediately before use; typical final organic solvent concentration ≤0.5–1% v/v for cellular systems.
• Analytical verification: Confirm concentration by UV–Vis (if chromophore known) or quantitative NMR/LC–MS against standards.
• Stability checks: Assess after at least one freeze–thaw and 24 h at working temperature.

Please consult the CoA/Spec Sheet or contact Technical Support for protocol guidance tailored to the confirmed identity of CER6-2’R-d.

Biological Roles

Biological functions or roles for CER6-2’R-d are not specified in the Product Data. Without a defined molecular identity, we cannot ascribe pathways, targets, or mechanistic roles.

Guidance for researchers

• If the reagent is intended as a biochemical probe or standard, confirm its identity, purity, and isomeric form via CoA before interpreting biological outcomes.
• Establish baseline controls: vehicle-only, heat-inactivated (if relevant), and orthogonal assay readouts to distinguish compound effects from solvent or assay artifacts.
• Verify stability in the assay medium (buffer, serum-containing media) over the assay timeframe by LC–MS to exclude decomposition products as confounders.

Research use note: For research use only; not for diagnostic, therapeutic, or clinical applications.

Buffer Applications

No buffer system details are provided for CER6-2’R-d, and its acid/base properties are not specified. Consequently, specific buffer recipes or pH ranges cannot be recommended for this item.

General practice

• If the reagent must be used in aqueous media, prepare a concentrated stock in a miscible organic solvent (e.g., DMSO) and dilute into the desired buffer with vigorous mixing; confirm absence of precipitation.
• Validate compatibility with common biological buffers (PBS, HEPES, Tris) by monitoring solubility and stability over the assay period.
• Filter-sterilize aqueous working solutions through 0.22 μm membranes if sterility is required.

Green Alternatives

Specific environmental, health, and safety (EHS) attributes for CER6-2’R-d are not available. In the absence of item-specific data, greener practice focuses on solvent choice and scale minimization.

• Prefer greener solvents for stock prep and workup when compatible:
  • Water, ethanol, isopropanol, ethyl acetate, MEK, 2-MeTHF, CPME.
  • Avoid or minimize chlorinated solvents (DCM/CHCl3) and DMF/NMP unless required by solubility.
• Process considerations:
  • Use microscale experiments to limit waste and establish solubility/stability.
  • Implement closed containers and cold storage to extend shelf life and reduce degradation waste.
• Energy and safety:
  • Store at the recommended -20 °C to maintain integrity and reduce repeat syntheses/purchases.
  • Prefer room-temperature reactions/assays and catalytic conditions when feasible.

Once the chemical identity and solvent compatibility are confirmed from the CoA, a tailored solvent substitution table (greener vs conventional) can be developed for your specific workflow.

Pharmaceutical Uses

No pharmacopeial status, excipient role, or formulation guidance is provided for CER6-2’R-d. This product is supplied strictly for research use only.

General considerations (research/manufacturing context)

• Do not use for human or veterinary applications.
• If exploring preformulation research, determine fundamental properties first (solubility, pKa, logP/logD, polymorphism) and generate a stability-indicating assay.
• If the material is amphiphilic or hydrophobic, consider enabling formulations for research use only (cyclodextrin inclusion, lipid-based carriers), validating stability and compatibility experimentally.

Physical Properties

Item-specific measured properties have not been provided in the Product Data.

• Appearance: Not specified for this item; refer to CoA/Spec Sheet.
• Melting point: Not specified for this item; refer to CoA/Spec Sheet.
• Boiling point: Not specified for this item; refer to CoA/Spec Sheet.
• Density: Not specified for this item; refer to CoA/Spec Sheet.
• Solubility: Not specified for this item; refer to CoA/Spec Sheet.
• LogP/logD: Not specified for this item; refer to CoA/Spec Sheet.
• pKa: Not specified for this item; refer to CoA/Spec Sheet.
• Refractive index: Not applicable unless liquid; not specified for this item.

Practical guidance (general)

• Start solubility screening with a small aliquot across common lab solvents relevant to your application tier: water, PBS, MeOH, EtOH, DMSO, DMF, acetonitrile, THF, isopropanol. Record concentration limits at room temperature and with gentle warming (≤40 °C) where compatible.
• If preparing concentrated DMSO stocks for bioassays, filter-sterilize (0.22 μm PTFE) and confirm stability by LC–MS after freeze–thaw.
• Hygroscopicity, light sensitivity, and volatility are unknown; handle in a dry, low-light environment until the item’s CoA clarifies stability.

Quality and Grades

• Grade/Purity: Not specified for this item; refer to CoA/Spec Sheet.

How to interpret and verify quality (general guidance)

• If labeled “research grade,” expect suitability for laboratory investigations but not for GMP or clinical use. Verify by HPLC/UPLC purity, LC–MS mass confirmation, and NMR identity.
• If low-UV absorbance or chromatography-grade performance is needed, request spectral baseline/UV cutoff data. In absence of such, pre-test for your detection wavelength.
• If the item includes a stabilizer (antioxidant, acid, base), this will appear on the CoA; stabilizers can influence bioassays and chromatography. None are specified here.
• Lot-specific documentation: Request the latest CoA for purity (%), residual solvents, water content (Karl Fischer), inorganics, and assay method details.

Practical QC on receipt

• Record lot number, appearance, and mass. If feasible, run a quick check: ESI–MS for m/z, and a short HPLC gradient to verify a single dominant peak at expected RT before committing to large experiments.

Reaction and Applications

Manufacturer-specified applications were not provided for CER6-2’R-d. Without structural information, specific synthetic or assay roles cannot be asserted for this item.

General guidance for life-science small molecules

• Potential research roles may include: biochemical probe, assay substrate/standard, pathway modulator in mechanistic studies, or calibration control in analytical workflows. Selection must be driven by the confirmed identity and purity on the CoA.
• If using in biological assays:
  • Prepare sterile-filtered stocks in DMSO or aqueous buffer, verify stability and lack of interference with detection modalities (absorbance/fluorescence/MS).
  • Perform preliminary concentration–response pilot studies to bound working ranges and solubility limits.
• If using in synthetic workflows:
  • Confirm compatibility with moisture, heat, and base/acid prior to scale-up; use small-scale scouting reactions.
  • For unknown functional groups, avoid strong nucleophiles/electrophiles until reactivity is clearer, and monitor by LC–MS/UPLC.

Please consult the latest CoA/Spec Sheet or contact Aladdin Scientific Technical Support with your intended application to ensure fit-for-purpose use.

Reaction Conditions

No reaction condition ranges (solvent, temperature, catalysts, or times) can be recommended for CER6-2’R-d without structural information.

General method-development approach

• Start with orthogonal solvent systems (aprotic polar vs protic vs nonpolar) at ambient temperature; escalate temperature cautiously while monitoring integrity by LC–MS.
• Use inert atmosphere (N2/Ar) until oxidative stability is known. Dry solvents and glassware if moisture sensitivity is suspected.
• If using in bioconjugation or labeling workflows, titrate reagent equivalents, buffer pH, and co-solvent percentage systematically and confirm product formation with MS.
• Document yields and mass balance meticulously to identify degradation or adsorption losses.

Safety and Handling

Hazard classification for this specific item has not been provided. Always consult the product’s SDS for authoritative information.

• GHS Classification, Signal word, H-statements, Pictograms: Not specified for this item; refer to SDS.
• General PPE: Wear lab coat, safety glasses or face shield, and appropriate chemically resistant gloves (e.g., nitrile). Use in a fume hood to avoid inhalation exposure.
• Handling tips:
  • Avoid dust/aerosol generation. Use sealed microtubes or vials when aliquoting.
  • Unknown reactivity and stability: keep away from strong oxidizers/reductants and acids/bases until compatibility is established.
  • If the compound could be moisture- or light-sensitive, minimize exposure and consider amber vials with desiccant.
• First aid (general):
  • Inhalation: Move to fresh air; seek medical attention if symptoms occur.
  • Skin/eye contact: Rinse with water for ≥15 minutes; remove contaminated clothing; seek medical advice.
  • Ingestion: Rinse mouth; do not induce vomiting; seek medical attention.
• Spill response: Absorb with inert material (vermiculite), collect in suitable waste container. Decontaminate area with compatible solvent/detergent.
• Waste: Dispose as chemical waste in accordance with institutional and local regulations.

Shipping/storage provided: Shipped on cold packs; store at -20 °C. See Storage & Reconstitution for more.

Solvent Selection

Item-specific solubility and polarity are not provided. The following is a practical, generic decision path to select solvents for small-molecule life-science reagents:

• Primary stock solvents to trial (ascending polarity/proticity): hexanes (hydrocarbon), EtOAc, MeCN, THF, acetone, MeOH, EtOH, isopropanol, DMF, DMSO, water/PBS.
• Suggested workflow:
  • Begin with 1–10 mg in 0.5–1.0 mL solvent; sonicate and/or warm to 30–40 °C.
  • If aqueous compatibility is needed, prepare a DMSO (or DMF) concentrate (10–100 mM) and dilute into buffer with vigorous mixing; keep final DMSO ≤1% v/v for cell-based assays when possible.
  • For lipid-like or amphiphilic materials, test co-solvent systems (e.g., MeOH:water, MeCN:water) or incorporate mild surfactants only if compatible with the assay.
• Filtration: Use PTFE or PVDF membranes for organic-rich solutions; use PES/nylon for aqueous systems after checking compatibility.
• Stability checks: Assess precipitation, color change, and LC–MS integrity after 24–48 h at intended storage temperature.

Note: Once the CoA identifies the structure, refine solvent choice using logP/logD, pKa, and HBD/HBA counts (Hansen/solubility parameter approach).

Storage and Reconstitution

• Storage conditions (from Product Data): Store at -20 °C. Shipments are sent in an ice chest with ice pads to maintain a cold chain.
• Appearance: Not specified for this item; refer to CoA/Spec Sheet.
• Reconstitution solvent: Not specified for this item; select based on solubility screening (see Solvent Selection). DMSO is a common first choice for small-molecule stocks when compatible.
• Aliquoting: Upon first opening, dispense into single-use or limited-use aliquots under dry, low-light conditions to minimize degradation and contamination.
• Light/moisture sensitivity: Not specified; as a precaution, store in amber vials with desiccant in a sealed container.
• Freeze–thaw: Minimize cycles. Thaw on ice or at room temperature, mix gently to redissolve any precipitate, and promptly return unused aliquots to -20 °C.
• Stability/shelf life: Not specified for this item; refer to CoA/Spec Sheet. Verify integrity periodically by LC–MS or HPLC.

Research use note: For research use only.

Structure and Identity

• Item name: CER6-2’R-d (SKU: C1446834)
• CAS: 2260670-10-6
• Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
• Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
• SMILES: Not specified for this item; refer to CoA/Spec Sheet.
• InChIKey: Not specified for this item; refer to CoA/Spec Sheet.
• Structural description: Not specified in the Product Data. Without a structure, specific functional groups, ring systems, or stereochemical features cannot be described.

Notes for users

• If your workflow requires unequivocal identity confirmation, request the current CoA/Spec Sheet for structural identifiers (SMILES/InChIKey), spectral data (1H/13C NMR, HRMS), and purity profile (HPLC/LC–MS).
• For database cross-referencing (e.g., PubChem, ChemSpider), use the CAS number provided and verify any returned structure against the product’s CoA.

Synthetic Utility

The synthetic roles and functional group chemistry of CER6-2’R-d cannot be described without its structure. No building-block features, leaving groups, or reactive handles are specified in the Product Data.

General guidance

• Prior to any use in synthesis, obtain structural details (CoA) and assess functional groups by spectroscopic analysis (NMR, IR, MS) to anticipate reactivity and protective-group needs.
• Conduct small-scale test reactions under mild conditions and monitor by LC–MS/UPLC to map stability against acids/bases, nucleophiles/electrophiles, and redox conditions.
• If chiral, confirm enantiomeric/diastereomeric purity by chiral HPLC before asymmetric transformations or stereosensitive assays.

Target Specificity

No target, antigen, enzyme, receptor, or pathway specificity is provided for CER6-2’R-d. Without a defined identity and validated bioactivity, no claims of specificity can be made.

If you intend to use this material as a probe or modulator

• Obtain or generate target engagement data (e.g., binding assays, activity modulation, thermal shift) and validate with orthogonal methods.
• Confirm identity and purity for the specific lot used to avoid misattribution of effects.